Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7543.098 | 0.9501 | 0.9306 | 1.4503 | |
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7543.098 | 0.8881 | 0.8428 | 1.4503 | |
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7543.098 | 0.4976 | 0.2360 | 1.4503 | |
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7543.098 | 0.8207 | 0.7452 | 1.4503 | |
| T47DKBLUC | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7544.092 | 1.0306 | 1.0549 | 1.1147 | |
| T47DKBLUC | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7544.092 | 0.8938 | 0.8083 | 1.1147 | |
| T47DKBLUC | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7544.092 | 1.0388 | 1.0694 | 1.1147 | |
| T47DKBLUC | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7544.092 | 0.9173 | 0.8509 | 1.1147 | |
| T47DKBLUC | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7544.092 | 1.0164 | 1.0294 | 1.1147 | |
| T47DKBLUC | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7544.092 | 0.9679 | 0.9424 | 1.1147 | |
| T47DKBLUC | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7544.092 | 0.9898 | 0.9817 | 1.1147 | |
| T47DKBLUC | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7544.092 | 0.9255 | 0.8657 | 1.1147 | |
| T47DKBLUC | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7544.092 | 0.9403 | 0.8926 | 1.1147 | |
| T47DKBLUC | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7544.098 | 1.0124 | 1.0200 | 1.2438 | |
| T47DKBLUC | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7544.098 | 0.9198 | 0.8700 | 1.2438 | |
| T47DKBLUC | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7544.098 | 0.9482 | 0.9163 | 1.2438 | |
| T47DKBLUC | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7544.098 | 0.9705 | 0.9525 | 1.2438 | |
| T47DKBLUC | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7544.098 | 0.9245 | 0.8776 | 1.2438 | |
| T47DKBLUC | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7544.098 | 0.9532 | 0.9245 | 1.2438 | |
| T47DKBLUC | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7544.098 | 0.8879 | 0.8176 | 1.2438 | |
| T47DKBLUC | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7544.098 | 0.7216 | 0.5385 | 1.2438 | |
| T47DKBLUC | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7544.098 | 0.0197 | -0.9149 | 1.2438 | |
| T47DKBLUC | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7545.092 | 1.0702 | 1.1434 | 0.9794 | |
| T47DKBLUC | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7545.092 | 1.0163 | 1.0333 | 0.9794 | |
| T47DKBLUC | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7545.092 | 1.0061 | 1.0126 | 0.9794 |