Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7542.098 | 0.5161 | 0.2037 | 1.3028 | |
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7542.098 | 0.0165 | -0.9143 | 1.3028 | |
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000307 | uM | 7543.071 | 1.0766 | 1.1090 | 1.3896 | |
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00154 | uM | 7543.071 | 1.1033 | 1.1466 | 1.3896 | |
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00768 | uM | 7543.071 | 1.0768 | 1.1094 | 1.3896 | |
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0384 | uM | 7543.071 | 1.0294 | 1.0421 | 1.3896 | |
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.192 | uM | 7543.071 | 0.9909 | 0.9869 | 1.3896 | |
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.96 | uM | 7543.071 | 0.8780 | 0.8212 | 1.3896 | |
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 4.8 | uM | 7543.071 | 0.8542 | 0.7855 | 1.3896 | |
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 24 | uM | 7543.071 | 0.0272 | -0.8507 | 1.3896 | |
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 120 | uM | 7543.071 | 0.0183 | -0.8878 | 1.3896 | |
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7543.091 | 1.0294 | 1.0395 | 1.4781 | |
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7543.091 | 1.0066 | 1.0089 | 1.4781 | |
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7543.091 | 0.9805 | 0.9736 | 1.4781 | |
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7543.091 | 0.9928 | 0.9902 | 1.4781 | |
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7543.091 | 0.9200 | 0.8903 | 1.4781 | |
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7543.091 | 0.8682 | 0.8177 | 1.4781 | |
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7543.091 | 0.8460 | 0.7860 | 1.4781 | |
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7543.091 | 0.8984 | 0.8601 | 1.4781 | |
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 133 | uM | 7543.091 | 0.3412 | -0.0338 | 1.4781 | |
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7543.098 | 1.0476 | 1.0652 | 1.4503 | |
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7543.098 | 0.9839 | 0.9777 | 1.4503 | |
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7543.098 | 0.9972 | 0.9961 | 1.4503 | |
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7543.098 | 0.9699 | 0.9584 | 1.4503 | |
| T47D | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7543.098 | 0.9114 | 0.8761 | 1.4503 |