Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 13.3 | uM | 10381.092 | 0.7981 | 0.7051 | 1.4137 | |
| SUM1315MO2 | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 66.7 | uM | 10381.092 | 0.7713 | 0.6644 | 1.4137 | |
| SUM149PT | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7530.091 | 1.0068 | 1.0065 | 2.0794 | |
| SUM149PT | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7530.091 | 1.1004 | 1.0942 | 2.0794 | |
| SUM149PT | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7530.091 | 0.9781 | 0.9788 | 2.0794 | |
| SUM149PT | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7530.091 | 1.0270 | 1.0258 | 2.0794 | |
| SUM149PT | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7530.091 | 1.0191 | 1.0183 | 2.0794 | |
| SUM149PT | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7530.091 | 0.7173 | 0.7047 | 2.0794 | |
| SUM149PT | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7530.091 | 0.6303 | 0.6019 | 2.0794 | |
| SUM149PT | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7530.091 | 0.0070 | -0.8157 | 2.0794 | |
| SUM149PT | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 133 | uM | 7530.091 | 0.0072 | -0.8137 | 2.0794 | |
| SUM159PT | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7531.091 | 1.1011 | 1.0590 | 3.3140 | |
| SUM159PT | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7531.091 | 1.0325 | 1.0194 | 3.3140 | |
| SUM159PT | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7531.091 | 1.0593 | 1.0351 | 3.3140 | |
| SUM159PT | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7531.091 | 1.0945 | 1.0553 | 3.3140 | |
| SUM159PT | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7531.091 | 1.0043 | 1.0026 | 3.3140 | |
| SUM159PT | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7531.091 | 1.0885 | 1.0519 | 3.3140 | |
| SUM159PT | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7531.091 | 0.0574 | -0.1554 | 3.3140 | |
| SUM159PT | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7531.091 | 0.0007 | -0.7788 | 3.3140 | |
| SUM159PT | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 133 | uM | 7531.091 | 0.0006 | -0.7888 | 3.3140 | |
| SUM159PT | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7531.098 | 1.1600 | 1.0872 | 3.4793 | |
| SUM159PT | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7531.098 | 0.9922 | 0.9955 | 3.4793 | |
| SUM159PT | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7531.098 | 1.0601 | 1.0338 | 3.4793 | |
| SUM159PT | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7531.098 | 1.0923 | 1.0514 | 3.4793 | |
| SUM159PT | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7531.098 | 1.0885 | 1.0493 | 3.4793 |