Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000307 | uM | 7512.071 | 0.9439 | 0.8824 | 0.9528 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00154 | uM | 7512.071 | 1.0343 | 1.0720 | 0.9528 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00768 | uM | 7512.071 | 0.9094 | 0.8103 | 0.9528 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0384 | uM | 7512.071 | 0.9854 | 0.9694 | 0.9528 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.192 | uM | 7512.071 | 0.8914 | 0.7727 | 0.9528 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.96 | uM | 7512.071 | 0.8833 | 0.7558 | 0.9528 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 4.8 | uM | 7512.071 | 0.7956 | 0.5733 | 0.9528 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 24 | uM | 7512.071 | 0.0297 | -0.9501 | 0.9528 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 120 | uM | 7512.071 | 0.0179 | -0.9707 | 0.9528 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7512.091 | 1.0364 | 1.0829 | 0.8817 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7512.091 | 1.0832 | 1.1897 | 0.8817 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7512.091 | 0.9723 | 0.9372 | 0.8817 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7512.091 | 1.0499 | 1.1136 | 0.8817 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7512.091 | 0.9188 | 0.8169 | 0.8817 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7512.091 | 0.7514 | 0.4463 | 0.8817 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7512.091 | 0.7645 | 0.4749 | 0.8817 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7512.091 | 0.8466 | 0.6558 | 0.8817 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 133 | uM | 7512.091 | 0.0627 | -0.9135 | 0.8817 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7512.098 | 0.9902 | 0.9793 | 0.9499 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7512.098 | 0.9646 | 0.9256 | 0.9499 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7512.098 | 0.9901 | 0.9791 | 0.9499 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7512.098 | 0.9343 | 0.8620 | 0.9499 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7512.098 | 0.8959 | 0.7815 | 0.9499 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7512.098 | 0.8794 | 0.7470 | 0.9499 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7512.098 | 0.7741 | 0.5275 | 0.9499 |