Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7510.098 | 0.8768 | 0.7423 | 0.9528 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7510.098 | 1.0829 | 1.1745 | 0.9528 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7510.098 | 0.8800 | 0.7490 | 0.9528 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7510.098 | 0.9142 | 0.8203 | 0.9528 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7510.098 | 0.9075 | 0.8062 | 0.9528 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7510.098 | 0.0356 | -0.9397 | 0.9528 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7510.098 | 0.0408 | -0.9304 | 0.9528 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7511.091 | 0.9884 | 0.9788 | 1.0995 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7511.091 | 0.9251 | 0.8633 | 1.0995 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7511.091 | 1.0035 | 1.0065 | 1.0995 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7511.091 | 0.9556 | 0.9191 | 1.0995 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7511.091 | 0.8735 | 0.7686 | 1.0995 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7511.091 | 0.7564 | 0.5515 | 1.0995 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7511.091 | 0.6120 | 0.2795 | 1.0995 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7511.091 | 0.0207 | -0.9411 | 1.0995 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 133 | uM | 7511.091 | 0.0249 | -0.9305 | 1.0995 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7511.098 | 0.9902 | 0.9837 | 1.2032 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7511.098 | 0.9355 | 0.8922 | 1.2032 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7511.098 | 0.9514 | 0.9189 | 1.2032 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7511.098 | 0.9462 | 0.9102 | 1.2032 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7511.098 | 0.9610 | 0.9349 | 1.2032 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7511.098 | 0.8516 | 0.7500 | 1.2032 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7511.098 | 0.7019 | 0.4902 | 1.2032 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7511.098 | 0.7173 | 0.5173 | 1.2032 | |
| MDA-MB-415 | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7511.098 | 0.2499 | -0.3683 | 1.2032 |