Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-134-VI | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.0000853 | uM | 7876.001 | 1.0158 | 1.0322 | 0.9806 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 7876.001 | 0.9622 | 0.9229 | 0.9806 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 7876.001 | 1.0317 | 1.0646 | 0.9806 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 7876.001 | 0.9653 | 0.9291 | 0.9806 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 7876.001 | 1.0137 | 1.0279 | 0.9806 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.267 | uM | 7876.001 | 0.3488 | -0.3167 | 0.9806 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 1.33 | uM | 7876.001 | 0.3570 | -0.3004 | 0.9806 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 6.67 | uM | 7876.001 | 0.4000 | -0.2144 | 0.9806 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 33.3 | uM | 7876.001 | 0.4221 | -0.1701 | 0.9806 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.0000853 | uM | 7877.001 | 1.0382 | 1.1795 | 0.4366 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 7877.001 | 0.9316 | 0.7006 | 0.4366 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 7877.001 | 1.0325 | 1.1522 | 0.4366 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 7877.001 | 0.9546 | 0.7980 | 0.4366 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 7877.001 | 1.0044 | 1.0200 | 0.4366 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.267 | uM | 7877.001 | 0.4315 | -0.7082 | 0.4366 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 1.33 | uM | 7877.001 | 0.4812 | -0.6256 | 0.4366 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 6.67 | uM | 7877.001 | 0.4812 | -0.6254 | 0.4366 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 33.3 | uM | 7877.001 | 0.4666 | -0.6510 | 0.4366 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.0000853 | uM | 10077.001 | 1.0110 | 1.0373 | 0.5941 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 10077.001 | 0.9379 | 0.7954 | 0.5941 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 10077.001 | 1.0457 | 1.1563 | 0.5941 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 10077.001 | 0.9657 | 0.8860 | 0.5941 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 10077.001 | 0.8710 | 0.5853 | 0.5941 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.267 | uM | 10077.001 | 0.9336 | 0.7814 | 0.5941 | |
| MDA-MB-134-VI | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 1.33 | uM | 10077.001 | 0.8288 | 0.4580 | 0.5941 |