Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | IKK16 | IKK | NFKB | 13.3 | uM | 7465.1 | 0.0079 | -0.9571 | 1.2603 | |
| HCC3153 | TNBC | Basal A | IKK16 | IKK | NFKB | 66.7 | uM | 7465.1 | 0.0062 | -0.9646 | 1.2603 | |
| HCC3153 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.000171 | uM | 7466.093 | 0.9974 | 0.9939 | 0.8543 | |
| HCC3153 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.000853 | uM | 7466.093 | 0.9755 | 0.9428 | 0.8543 | |
| HCC3153 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.00427 | uM | 7466.093 | 0.9969 | 0.9928 | 0.8543 | |
| HCC3153 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.0213 | uM | 7466.093 | 1.0173 | 1.0405 | 0.8543 | |
| HCC3153 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.107 | uM | 7466.093 | 0.9793 | 0.9517 | 0.8543 | |
| HCC3153 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.533 | uM | 7466.093 | 0.9910 | 0.9789 | 0.8543 | |
| HCC3153 | TNBC | Basal A | IKK16 | IKK | NFKB | 2.67 | uM | 7466.093 | 0.8560 | 0.6672 | 0.8543 | |
| HCC3153 | TNBC | Basal A | IKK16 | IKK | NFKB | 13.3 | uM | 7466.093 | 0.0129 | -0.9877 | 0.8543 | |
| HCC3153 | TNBC | Basal A | IKK16 | IKK | NFKB | 66.7 | uM | 7466.093 | 0.0120 | -0.9887 | 0.8543 | |
| HCC3153 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.000171 | uM | 10577.1 | 1.0319 | 1.0730 | 0.8774 | |
| HCC3153 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.000853 | uM | 10577.1 | 0.9844 | 0.9644 | 0.8774 | |
| HCC3153 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.00427 | uM | 10577.1 | 0.9976 | 0.9946 | 0.8774 | |
| HCC3153 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.0213 | uM | 10577.1 | 1.0472 | 1.1080 | 0.8774 | |
| HCC3153 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.107 | uM | 10577.1 | 1.0485 | 1.1110 | 0.8774 | |
| HCC3153 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.533 | uM | 10577.1 | 1.0066 | 1.0150 | 0.8774 | |
| HCC3153 | TNBC | Basal A | IKK16 | IKK | NFKB | 2.67 | uM | 10577.1 | 1.0105 | 1.0239 | 0.8774 | |
| HCC3153 | TNBC | Basal A | IKK16 | IKK | NFKB | 13.3 | uM | 10577.1 | 0.3500 | -0.3955 | 0.8774 | |
| HCC3153 | TNBC | Basal A | IKK16 | IKK | NFKB | 66.7 | uM | 10577.1 | 0.0113 | -0.9879 | 0.8774 | |
| HCC38 | TNBC | Basal B | IKK16 | IKK | NFKB | 0.000171 | uM | 7468.093 | 0.9854 | 0.9792 | 1.4007 | |
| HCC38 | TNBC | Basal B | IKK16 | IKK | NFKB | 0.000853 | uM | 7468.093 | 0.9496 | 0.9275 | 1.4007 | |
| HCC38 | TNBC | Basal B | IKK16 | IKK | NFKB | 0.00427 | uM | 7468.093 | 0.9997 | 0.9995 | 1.4007 | |
| HCC38 | TNBC | Basal B | IKK16 | IKK | NFKB | 0.0213 | uM | 7468.093 | 0.9941 | 0.9915 | 1.4007 | |
| HCC38 | TNBC | Basal B | IKK16 | IKK | NFKB | 0.107 | uM | 7468.093 | 0.9949 | 0.9928 | 1.4007 |