Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1954 | HER2amp | Basal A | IKK16 | IKK | NFKB | 0.000171 | uM | 10469.1 | 0.9949 | 0.9935 | 1.5717 | |
| HCC1954 | HER2amp | Basal A | IKK16 | IKK | NFKB | 0.000853 | uM | 10469.1 | 0.9913 | 0.9888 | 1.5717 | |
| HCC1954 | HER2amp | Basal A | IKK16 | IKK | NFKB | 0.00427 | uM | 10469.1 | 0.9848 | 0.9806 | 1.5717 | |
| HCC1954 | HER2amp | Basal A | IKK16 | IKK | NFKB | 0.0213 | uM | 10469.1 | 1.0191 | 1.0242 | 1.5717 | |
| HCC1954 | HER2amp | Basal A | IKK16 | IKK | NFKB | 0.107 | uM | 10469.1 | 1.0126 | 1.0160 | 1.5717 | |
| HCC1954 | HER2amp | Basal A | IKK16 | IKK | NFKB | 0.533 | uM | 10469.1 | 0.9398 | 0.9226 | 1.5717 | |
| HCC1954 | HER2amp | Basal A | IKK16 | IKK | NFKB | 2.67 | uM | 10469.1 | 0.4665 | 0.2312 | 1.5717 | |
| HCC1954 | HER2amp | Basal A | IKK16 | IKK | NFKB | 13.3 | uM | 10469.1 | 0.0083 | -0.9054 | 1.5717 | |
| HCC1954 | HER2amp | Basal A | IKK16 | IKK | NFKB | 66.7 | uM | 10469.1 | 0.0086 | -0.9028 | 1.5717 | |
| HCC2185 | TNBC | Luminal | IKK16 | IKK | NFKB | 0.000171 | uM | 7462.093 | 1.0277 | 1.1273 | 0.4426 | |
| HCC2185 | TNBC | Luminal | IKK16 | IKK | NFKB | 0.000853 | uM | 7462.093 | 0.9834 | 0.9258 | 0.4426 | |
| HCC2185 | TNBC | Luminal | IKK16 | IKK | NFKB | 0.00427 | uM | 7462.093 | 1.0019 | 1.0086 | 0.4426 | |
| HCC2185 | TNBC | Luminal | IKK16 | IKK | NFKB | 0.0213 | uM | 7462.093 | 1.0013 | 1.0059 | 0.4426 | |
| HCC2185 | TNBC | Luminal | IKK16 | IKK | NFKB | 0.107 | uM | 7462.093 | 0.9875 | 0.9439 | 0.4426 | |
| HCC2185 | TNBC | Luminal | IKK16 | IKK | NFKB | 0.533 | uM | 7462.093 | 1.0067 | 1.0302 | 0.4426 | |
| HCC2185 | TNBC | Luminal | IKK16 | IKK | NFKB | 2.67 | uM | 7462.093 | 1.0569 | 1.2665 | 0.4426 | |
| HCC2185 | TNBC | Luminal | IKK16 | IKK | NFKB | 13.3 | uM | 7462.093 | 0.0117 | -0.9999 | 0.4426 | |
| HCC2185 | TNBC | Luminal | IKK16 | IKK | NFKB | 66.7 | uM | 7462.093 | 0.0109 | -0.9999 | 0.4426 | |
| HCC3153 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.000171 | uM | 7465.1 | 1.0738 | 1.1162 | 1.2603 | |
| HCC3153 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.000853 | uM | 7465.1 | 0.8815 | 0.8095 | 1.2603 | |
| HCC3153 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.00427 | uM | 7465.1 | 0.9192 | 0.8706 | 1.2603 | |
| HCC3153 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.0213 | uM | 7465.1 | 0.9437 | 0.9102 | 1.2603 | |
| HCC3153 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.107 | uM | 7465.1 | 0.9802 | 0.9685 | 1.2603 | |
| HCC3153 | TNBC | Basal A | IKK16 | IKK | NFKB | 0.533 | uM | 7465.1 | 0.8732 | 0.7960 | 1.2603 | |
| HCC3153 | TNBC | Basal A | IKK16 | IKK | NFKB | 2.67 | uM | 7465.1 | 0.7499 | 0.5917 | 1.2603 |