Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 7875.001 | 1.1151 | 1.1550 | 1.4600 | |
| MCF7 | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 7875.001 | 1.0232 | 1.0317 | 1.4600 | |
| MCF7 | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 7875.001 | 0.8347 | 0.7672 | 1.4600 | |
| MCF7 | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.267 | uM | 7875.001 | 0.7243 | 0.6036 | 1.4600 | |
| MCF7 | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 1.33 | uM | 7875.001 | 0.6966 | 0.5613 | 1.4600 | |
| MCF7 | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 6.67 | uM | 7875.001 | 0.6251 | 0.4496 | 1.4600 | |
| MCF7 | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 33.3 | uM | 7875.001 | 0.1842 | -0.3722 | 1.4600 | |
| MCF7 | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.0000853 | uM | 9583.001 | 1.0362 | 1.0640 | 1.1288 | |
| MCF7 | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 9583.001 | 0.9448 | 0.9019 | 1.1288 | |
| MCF7 | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 9583.001 | 1.0096 | 1.0170 | 1.1288 | |
| MCF7 | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 9583.001 | 1.0212 | 1.0375 | 1.1288 | |
| MCF7 | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 9583.001 | 0.9078 | 0.8357 | 1.1288 | |
| MCF7 | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.267 | uM | 9583.001 | 0.8015 | 0.6439 | 1.1288 | |
| MCF7 | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 1.33 | uM | 9583.001 | 0.7187 | 0.4925 | 1.1288 | |
| MCF7 | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 6.67 | uM | 9583.001 | 0.7547 | 0.5586 | 1.1288 | |
| MCF7 | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 33.3 | uM | 9583.001 | 0.5787 | 0.2319 | 1.1288 | |
| MCF7 | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.0000853 | uM | 10073.001 | 1.0126 | 1.0426 | 0.5923 | |
| MCF7 | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 10073.001 | 0.9633 | 0.8777 | 0.5923 | |
| MCF7 | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 10073.001 | 1.0009 | 1.0030 | 0.5923 | |
| MCF7 | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 10073.001 | 0.9910 | 0.9697 | 0.5923 | |
| MCF7 | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 10073.001 | 0.9196 | 0.7360 | 0.5923 | |
| MCF7 | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 0.267 | uM | 10073.001 | 0.8764 | 0.6007 | 0.5923 | |
| MCF7 | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 1.33 | uM | 10073.001 | 0.8590 | 0.5473 | 0.5923 | |
| MCF7 | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 6.67 | uM | 10073.001 | 0.8239 | 0.4421 | 0.5923 | |
| MCF7 | HR+ | Luminal | GSK923295 | CENPE | Kinesin | 33.3 | uM | 10073.001 | 0.5253 | -0.3255 | 0.5923 |