Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7537.098 | 0.8597 | 0.8462 | 1.8887 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7537.098 | 0.5691 | 0.4839 | 1.8887 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7537.098 | 0.2527 | -0.0346 | 1.8887 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7537.098 | 0.0276 | -0.7012 | 1.8887 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7537.098 | 0.0134 | -0.7965 | 1.8887 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7539.092 | 1.0099 | 1.0162 | 1.2233 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7539.092 | 0.9625 | 0.9384 | 1.2233 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7539.092 | 0.6938 | 0.4833 | 1.2233 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7539.092 | 1.0206 | 1.0336 | 1.2233 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7539.092 | 1.0054 | 1.0088 | 1.2233 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7539.092 | 0.8748 | 0.7928 | 1.2233 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7539.092 | 0.7565 | 0.5921 | 1.2233 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7539.092 | 0.5711 | 0.2651 | 1.2233 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7539.092 | 0.6868 | 0.4712 | 1.2233 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7539.098 | 0.9552 | 0.9444 | 1.6240 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7539.098 | 0.8753 | 0.8425 | 1.6240 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7539.098 | 0.8990 | 0.8731 | 1.6240 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7539.098 | 0.9293 | 0.9117 | 1.6240 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7539.098 | 0.9462 | 0.9331 | 1.6240 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7539.098 | 0.7794 | 0.7155 | 1.6240 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7539.098 | 0.6159 | 0.4840 | 1.6240 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7539.098 | 0.0361 | -0.7412 | 1.6240 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7539.098 | 0.0312 | -0.7635 | 1.6240 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7540.09 | 0.9126 | 0.7037 | 0.5702 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7540.09 | 1.0050 | 1.0175 | 0.5702 |