Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 10151.001 | 1.1029 | 1.5238 | 0.4212 | |
| UACC-812 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 10151.001 | 0.9821 | 0.9162 | 0.4212 | |
| UACC-812 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 10151.001 | 0.5550 | -0.5058 | 0.4212 | |
| UACC-812 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.267 | uM | 10151.001 | 0.5462 | -0.5241 | 0.4212 | |
| UACC-812 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 1.33 | uM | 10151.001 | 0.5412 | -0.5345 | 0.4212 | |
| UACC-812 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 6.67 | uM | 10151.001 | 0.6378 | -0.3124 | 0.4212 | |
| UACC-812 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 33.3 | uM | 10151.001 | 0.6589 | -0.2573 | 0.4212 | |
| UACC-812 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.0000853 | uM | 10267.001 | 1.1326 | 1.7397 | 0.3957 | |
| UACC-812 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 10267.001 | 1.0930 | 1.5042 | 0.3957 | |
| UACC-812 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 10267.001 | 1.1071 | 1.5864 | 0.3957 | |
| UACC-812 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 10267.001 | 0.9513 | 0.7628 | 0.3957 | |
| UACC-812 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 10267.001 | 0.5691 | -0.5189 | 0.3957 | |
| UACC-812 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.267 | uM | 10267.001 | 0.4954 | -0.6612 | 0.3957 | |
| UACC-812 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 1.33 | uM | 10267.001 | 0.5925 | -0.4673 | 0.3957 | |
| UACC-812 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 6.67 | uM | 10267.001 | 0.5911 | -0.4705 | 0.3957 | |
| UACC-812 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 33.3 | uM | 10267.001 | 0.6150 | -0.4146 | 0.3957 | |
| UACC-893 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.0000853 | uM | 9045.001 | 1.0588 | 1.1212 | 0.9719 | |
| UACC-893 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 9045.001 | 0.9299 | 0.8560 | 0.9719 | |
| UACC-893 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 9045.001 | 1.1303 | 1.2686 | 0.9719 | |
| UACC-893 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 9045.001 | 0.7870 | 0.5631 | 0.9719 | |
| UACC-893 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 9045.001 | 0.8994 | 0.7933 | 0.9719 | |
| UACC-893 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.267 | uM | 9045.001 | 0.3985 | -0.2239 | 0.9719 | |
| UACC-893 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 1.33 | uM | 9045.001 | 0.4485 | -0.1237 | 0.9719 | |
| UACC-893 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 6.67 | uM | 9045.001 | 0.5335 | 0.0478 | 0.9719 | |
| UACC-893 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 33.3 | uM | 9045.001 | 0.4959 | -0.0282 | 0.9719 |