Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7540.09 | 0.7899 | 0.3226 | 0.5702 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7540.09 | 1.0524 | 1.1873 | 0.5702 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7540.09 | 0.9380 | 0.7876 | 0.5702 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7540.09 | 0.4741 | -0.4598 | 0.5702 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7540.09 | 0.1579 | -0.9215 | 0.5702 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7540.09 | 0.2956 | -0.7641 | 0.5702 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 133 | uM | 7540.09 | 0.9107 | 0.6975 | 0.5702 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000307 | uM | 7541.071 | 1.0965 | 1.1413 | 1.3491 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00154 | uM | 7541.071 | 0.9842 | 0.9766 | 1.3491 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00768 | uM | 7541.071 | 0.9943 | 0.9915 | 1.3491 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0384 | uM | 7541.071 | 1.0298 | 1.0441 | 1.3491 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.192 | uM | 7541.071 | 0.9246 | 0.8871 | 1.3491 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.96 | uM | 7541.071 | 0.8678 | 0.8005 | 1.3491 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 4.8 | uM | 7541.071 | 0.7296 | 0.5833 | 1.3491 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 24 | uM | 7541.071 | 0.0745 | -0.7081 | 1.3491 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 120 | uM | 7541.071 | 0.0444 | -0.8014 | 1.3491 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7541.091 | 1.0313 | 1.0441 | 1.4119 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7541.091 | 1.0323 | 1.0455 | 1.4119 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7541.091 | 0.9789 | 0.9700 | 1.4119 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7541.091 | 0.9981 | 0.9974 | 1.4119 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7541.091 | 0.9757 | 0.9654 | 1.4119 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7541.091 | 0.8202 | 0.7381 | 1.4119 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7541.091 | 0.4266 | 0.0940 | 1.4119 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7541.091 | 0.2439 | -0.2638 | 1.4119 | |
| SUM52PE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 133 | uM | 7541.091 | 0.0189 | -0.8795 | 1.4119 |