Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7536.09 | 0.2165 | -0.4863 | 1.1257 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7536.09 | 0.3824 | -0.1485 | 1.1257 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 133 | uM | 7536.09 | 0.6996 | 0.4562 | 1.1257 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 0.000307 | uM | 7537.071 | 0.9821 | 0.9817 | 1.9607 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 0.00154 | uM | 7537.071 | 0.9454 | 0.9436 | 1.9607 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 0.00768 | uM | 7537.071 | 0.9767 | 0.9761 | 1.9607 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 0.0384 | uM | 7537.071 | 0.9385 | 0.9363 | 1.9607 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 0.192 | uM | 7537.071 | 0.8341 | 0.8233 | 1.9607 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 0.96 | uM | 7537.071 | 0.3921 | 0.2406 | 1.9607 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 4.8 | uM | 7537.071 | 0.2590 | 0.0042 | 1.9607 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 24 | uM | 7537.071 | 0.0192 | -0.7340 | 1.9607 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 120 | uM | 7537.071 | 0.0097 | -0.8120 | 1.9607 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7537.091 | 0.9549 | 0.9549 | 2.0227 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7537.091 | 0.9982 | 0.9982 | 2.0227 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7537.091 | 0.9938 | 0.9938 | 2.0227 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7537.091 | 0.9753 | 0.9754 | 2.0227 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7537.091 | 0.8953 | 0.8936 | 2.0227 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7537.091 | 0.4255 | 0.3109 | 2.0227 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7537.091 | 0.1838 | -0.1343 | 2.0227 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7537.091 | 0.1031 | -0.3495 | 2.0227 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 133 | uM | 7537.091 | 0.0061 | -0.8389 | 2.0227 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7537.098 | 0.9878 | 0.9870 | 1.8887 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7537.098 | 0.9992 | 0.9991 | 1.8887 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7537.098 | 0.9651 | 0.9627 | 1.8887 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7537.098 | 0.9349 | 0.9300 | 1.8887 |