Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM225CWN | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7534.098 | 0.0534 | -0.9147 | 0.9286 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7535.092 | 1.0332 | 1.0588 | 1.1267 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7535.092 | 0.8980 | 0.8179 | 1.1267 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7535.092 | 0.9134 | 0.8455 | 1.1267 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7535.092 | 0.9539 | 0.9180 | 1.1267 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7535.092 | 0.9754 | 0.9562 | 1.1267 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7535.092 | 0.7481 | 0.5458 | 1.1267 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7535.092 | 0.2759 | -0.3623 | 1.1267 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7535.092 | 0.1271 | -0.6795 | 1.1267 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7535.092 | 0.0152 | -0.9514 | 1.1267 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7535.098 | 0.9675 | 0.9353 | 1.0037 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7535.098 | 0.9138 | 0.8283 | 1.0037 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7535.098 | 1.0094 | 1.0187 | 1.0037 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7535.098 | 0.9377 | 0.8758 | 1.0037 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7535.098 | 0.9082 | 0.8171 | 1.0037 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7535.098 | 0.8611 | 0.7232 | 1.0037 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7535.098 | 0.3983 | -0.2006 | 1.0037 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7535.098 | 0.0933 | -0.8117 | 1.0037 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7535.098 | 0.0169 | -0.9658 | 1.0037 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7536.09 | 0.8875 | 0.7988 | 1.1257 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7536.09 | 1.0187 | 1.0332 | 1.1257 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7536.09 | 0.8483 | 0.7281 | 1.1257 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7536.09 | 0.9721 | 0.9503 | 1.1257 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7536.09 | 0.9305 | 0.8760 | 1.1257 | |
| SUM229PE | TNBC | - | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7536.09 | 0.8937 | 0.8099 | 1.1257 |