Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7518.098 | 1.0361 | 1.0445 | 1.6108 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7518.098 | 0.9438 | 0.9294 | 1.6108 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7518.098 | 0.9809 | 0.9763 | 1.6108 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7518.098 | 0.9008 | 0.8744 | 1.6108 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7518.098 | 0.9050 | 0.8798 | 1.6108 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7518.098 | 0.8795 | 0.8468 | 1.6108 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7518.098 | 0.3147 | -0.0244 | 1.6108 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7518.098 | 0.8813 | 0.8491 | 1.6108 | |
| MX1 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.000307 | uM | 7523.071 | 0.8737 | 0.7461 | 0.9945 | |
| MX1 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.00154 | uM | 7523.071 | 0.9868 | 0.9734 | 0.9945 | |
| MX1 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.00768 | uM | 7523.071 | 0.9848 | 0.9694 | 0.9945 | |
| MX1 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.0384 | uM | 7523.071 | 0.9428 | 0.8850 | 0.9945 | |
| MX1 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.192 | uM | 7523.071 | 0.8666 | 0.7317 | 0.9945 | |
| MX1 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.96 | uM | 7523.071 | 0.9563 | 0.9121 | 0.9945 | |
| MX1 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 4.8 | uM | 7523.071 | 0.7683 | 0.5343 | 0.9945 | |
| MX1 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 24 | uM | 7523.071 | 0.0298 | -0.9416 | 0.9945 | |
| MX1 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 120 | uM | 7523.071 | 0.0091 | -0.9822 | 0.9945 | |
| MX1 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7523.091 | 0.9463 | 0.8845 | 0.9283 | |
| MX1 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7523.091 | 0.9226 | 0.8337 | 0.9283 | |
| MX1 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7523.091 | 0.9825 | 0.9622 | 0.9283 | |
| MX1 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7523.091 | 0.9107 | 0.8082 | 0.9283 | |
| MX1 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7523.091 | 0.9277 | 0.8446 | 0.9283 | |
| MX1 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7523.091 | 0.8934 | 0.7713 | 0.9283 | |
| MX1 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7523.091 | 0.8734 | 0.7285 | 0.9283 | |
| MX1 | Unknown | Unknown | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7523.091 | 0.0138 | -0.9802 | 0.9283 |