Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7517.098 | 1.0037 | 1.0057 | 1.2851 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7517.098 | 1.0425 | 1.0658 | 1.2851 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7517.098 | 0.9907 | 0.9856 | 1.2851 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7517.098 | 0.8687 | 0.7926 | 1.2851 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7517.098 | 0.0904 | -0.6918 | 1.2851 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7517.098 | 0.4793 | 0.1284 | 1.2851 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.000307 | uM | 7518.071 | 1.0444 | 1.0596 | 1.4797 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.00154 | uM | 7518.071 | 1.0853 | 1.1138 | 1.4797 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.00768 | uM | 7518.071 | 1.0525 | 1.0704 | 1.4797 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.0384 | uM | 7518.071 | 1.0234 | 1.0314 | 1.4797 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.192 | uM | 7518.071 | 0.9863 | 0.9815 | 1.4797 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.96 | uM | 7518.071 | 0.9995 | 0.9993 | 1.4797 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 4.8 | uM | 7518.071 | 0.9387 | 0.9163 | 1.4797 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 24 | uM | 7518.071 | 0.0902 | -0.6065 | 1.4797 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 120 | uM | 7518.071 | 0.1080 | -0.5557 | 1.4797 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7518.091 | 0.9304 | 0.9128 | 1.6174 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7518.091 | 1.0111 | 1.0137 | 1.6174 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7518.091 | 0.9683 | 0.9605 | 1.6174 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 7518.091 | 0.9956 | 0.9945 | 1.6174 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.213 | uM | 7518.091 | 0.9212 | 0.9010 | 1.6174 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7518.091 | 0.8456 | 0.8031 | 1.6174 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7518.091 | 0.7828 | 0.7190 | 1.6174 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7518.091 | 0.8011 | 0.7437 | 1.6174 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 133 | uM | 7518.091 | 0.3209 | -0.0096 | 1.6174 | |
| MDA-MB-453 | TNBC | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7518.098 | 0.9858 | 0.9823 | 1.6108 |