Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 7896.001 | 1.0078 | 1.0130 | 1.1912 | |
| MDA-MB-361 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 7896.001 | 1.0413 | 1.0692 | 1.1912 | |
| MDA-MB-361 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 7896.001 | 0.9899 | 0.9830 | 1.1912 | |
| MDA-MB-361 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 7896.001 | 0.7106 | 0.5013 | 1.1912 | |
| MDA-MB-361 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.267 | uM | 7896.001 | 0.3120 | -0.2477 | 1.1912 | |
| MDA-MB-361 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 1.33 | uM | 7896.001 | 0.3833 | -0.1059 | 1.1912 | |
| MDA-MB-361 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 6.67 | uM | 7896.001 | 0.3584 | -0.1548 | 1.1912 | |
| MDA-MB-361 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 33.3 | uM | 7896.001 | 0.3327 | -0.2061 | 1.1912 | |
| MDA-MB-361 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.0000853 | uM | 9648.001 | 1.0008 | 1.0025 | 0.6289 | |
| MDA-MB-361 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 9648.001 | 0.9878 | 0.9612 | 0.6289 | |
| MDA-MB-361 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 9648.001 | 0.9993 | 0.9977 | 0.6289 | |
| MDA-MB-361 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 9648.001 | 1.0338 | 1.1087 | 0.6289 | |
| MDA-MB-361 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 9648.001 | 0.5181 | -0.2970 | 0.6289 | |
| MDA-MB-361 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.267 | uM | 9648.001 | 0.4585 | -0.4213 | 0.6289 | |
| MDA-MB-361 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 1.33 | uM | 9648.001 | 0.4661 | -0.4060 | 0.6289 | |
| MDA-MB-361 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 6.67 | uM | 9648.001 | 0.4649 | -0.4084 | 0.6289 | |
| MDA-MB-361 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 33.3 | uM | 9648.001 | 0.4018 | -0.5309 | 0.6289 | |
| MDA-MB-361 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.0000853 | uM | 10095.001 | 0.9493 | 0.8883 | 0.9049 | |
| MDA-MB-361 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.000427 | uM | 10095.001 | 0.9529 | 0.8962 | 0.9049 | |
| MDA-MB-361 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.00213 | uM | 10095.001 | 0.9670 | 0.9273 | 0.9049 | |
| MDA-MB-361 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.0107 | uM | 10095.001 | 1.0004 | 1.0009 | 0.9049 | |
| MDA-MB-361 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.0533 | uM | 10095.001 | 0.4424 | -0.1880 | 0.9049 | |
| MDA-MB-361 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 0.267 | uM | 10095.001 | 0.4490 | -0.1746 | 0.9049 | |
| MDA-MB-361 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 1.33 | uM | 10095.001 | 0.4383 | -0.1963 | 0.9049 | |
| MDA-MB-361 | HER2amp | Luminal | GSK923295 | CENPE | Kinesin | 6.67 | uM | 10095.001 | 0.4572 | -0.1579 | 0.9049 |