Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 600MPE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 5899.09 | 0.9660 | 0.9346 | 1.0401 | |
| 600MPE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.213 | uM | 5899.09 | 0.9155 | 0.8373 | 1.0401 | |
| 600MPE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 1.07 | uM | 5899.09 | 0.5927 | 0.2095 | 1.0401 | |
| 600MPE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 5.33 | uM | 5899.09 | 0.5580 | 0.1413 | 1.0401 | |
| 600MPE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 26.7 | uM | 5899.09 | 0.5407 | 0.1073 | 1.0401 | |
| 600MPE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 133 | uM | 5899.09 | 0.5657 | 0.1566 | 1.0401 | |
| 600MPE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 5899.098 | 0.9207 | 0.8554 | 1.1012 | |
| 600MPE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 5899.098 | 0.9738 | 0.9523 | 1.1012 | |
| 600MPE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 5899.098 | 0.9210 | 0.8560 | 1.1012 | |
| 600MPE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 5899.098 | 0.9081 | 0.8323 | 1.1012 | |
| 600MPE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 5899.098 | 0.8597 | 0.7435 | 1.1012 | |
| 600MPE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 5899.098 | 0.6220 | 0.2996 | 1.1012 | |
| 600MPE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 5899.098 | 0.3970 | -0.1357 | 1.1012 | |
| 600MPE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 5899.098 | 0.2126 | -0.5098 | 1.1012 | |
| 600MPE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 5899.098 | 0.0472 | -0.8751 | 1.1012 | |
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 5900.092 | 1.0446 | 1.0334 | 2.6334 | |
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 5900.092 | 0.9871 | 0.9901 | 2.6334 | |
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 5900.092 | 0.9800 | 0.9848 | 2.6334 | |
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 5900.092 | 1.0079 | 1.0060 | 2.6334 | |
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 5900.092 | 1.0107 | 1.0081 | 2.6334 | |
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 5900.092 | 0.9009 | 0.9223 | 2.6334 | |
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 5900.092 | 0.7041 | 0.7505 | 2.6334 | |
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 5900.092 | 0.0255 | -0.5037 | 2.6334 | |
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 5900.092 | 0.0170 | -0.5748 | 2.6334 | |
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 5900.098 | 0.9837 | 0.9857 | 2.2937 |