Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 5900.098 | 1.0547 | 1.0470 | 2.2937 | |
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 5900.098 | 1.0452 | 1.0389 | 2.2937 | |
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 5900.098 | 1.0719 | 1.0614 | 2.2937 | |
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 5900.098 | 1.0005 | 1.0005 | 2.2937 | |
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 5900.098 | 0.9577 | 0.9627 | 2.2937 | |
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 5900.098 | 0.2633 | 0.1179 | 2.2937 | |
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 5900.098 | 0.0153 | -0.6767 | 2.2937 | |
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 5900.098 | 0.0045 | -0.8099 | 2.2937 | |
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 5901.07 | 1.0060 | 1.0062 | 1.9178 | |
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 5901.07 | 0.9898 | 0.9893 | 1.9178 | |
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 5901.07 | 0.9586 | 0.9564 | 1.9178 | |
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 5901.07 | 0.9709 | 0.9694 | 1.9178 | |
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 5901.07 | 0.9144 | 0.9089 | 1.9178 | |
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 5901.07 | 0.9278 | 0.9234 | 1.9178 | |
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 5901.07 | 0.6341 | 0.5772 | 1.9178 | |
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 5901.07 | 0.6078 | 0.5427 | 1.9178 | |
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 5901.07 | 0.4994 | 0.3924 | 1.9178 | |
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 5901.091 | 1.0238 | 1.0246 | 1.9229 | |
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 5901.091 | 1.0027 | 1.0029 | 1.9229 | |
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 5901.091 | 0.9704 | 0.9690 | 1.9229 | |
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 5901.091 | 1.0162 | 1.0168 | 1.9229 | |
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 0.213 | uM | 5901.091 | 0.9529 | 0.9505 | 1.9229 | |
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 1.07 | uM | 5901.091 | 0.8696 | 0.8598 | 1.9229 | |
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 5.33 | uM | 5901.091 | 0.2612 | -0.0049 | 1.9229 | |
| AU565 | HER2amp | Luminal | GSK1838705A | IGF1R | RTK | 26.7 | uM | 5901.091 | 0.7465 | 0.7179 | 1.9229 |