Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC202 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 33.3 | uM | 7841.001 | 0.3224 | -0.7519 | 0.5424 | |
| HCC202 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.0000853 | uM | 7844.001 | 0.9468 | 0.6729 | 0.3060 | |
| HCC202 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.000427 | uM | 7844.001 | 0.9312 | 0.5845 | 0.3060 | |
| HCC202 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.00213 | uM | 7844.001 | 0.9532 | 0.7101 | 0.3060 | |
| HCC202 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.0107 | uM | 7844.001 | 0.7905 | -0.0725 | 0.3060 | |
| HCC202 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.0533 | uM | 7844.001 | 0.7574 | -0.1934 | 0.3060 | |
| HCC202 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.267 | uM | 7844.001 | 0.7959 | -0.0514 | 0.3060 | |
| HCC202 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 1.33 | uM | 7844.001 | 0.9765 | 0.8505 | 0.3060 | |
| HCC202 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 6.67 | uM | 7844.001 | 0.7306 | -0.2832 | 0.3060 | |
| HCC202 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 33.3 | uM | 7844.001 | 0.0648 | -0.9997 | 0.3060 | |
| HCC202 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.0000853 | uM | 9402.001 | 0.7764 | 0.3604 | 0.6567 | |
| HCC202 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.000427 | uM | 9402.001 | 0.7605 | 0.3183 | 0.6567 | |
| HCC202 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.00213 | uM | 9402.001 | 0.7492 | 0.2885 | 0.6567 | |
| HCC202 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.0107 | uM | 9402.001 | 0.7330 | 0.2462 | 0.6567 | |
| HCC202 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.0533 | uM | 9402.001 | 0.5849 | -0.1163 | 0.6567 | |
| HCC202 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 0.267 | uM | 9402.001 | 0.5730 | -0.1435 | 0.6567 | |
| HCC202 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 1.33 | uM | 9402.001 | 0.6950 | 0.1493 | 0.6567 | |
| HCC202 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 6.67 | uM | 9402.001 | 0.5188 | -0.2638 | 0.6567 | |
| HCC202 | HER2amp | Luminal | GSK461364 | PLK1 | PLK | 33.3 | uM | 9402.001 | 0.3649 | -0.5692 | 0.6567 | |
| HCC2185 | TNBC | Luminal | GSK461364 | PLK1 | PLK | 0.0000853 | uM | 7848.001 | 0.9833 | 0.9272 | 0.4548 | |
| HCC2185 | TNBC | Luminal | GSK461364 | PLK1 | PLK | 0.000427 | uM | 7848.001 | 1.0747 | 1.3434 | 0.4548 | |
| HCC2185 | TNBC | Luminal | GSK461364 | PLK1 | PLK | 0.00213 | uM | 7848.001 | 0.9580 | 0.8201 | 0.4548 | |
| HCC2185 | TNBC | Luminal | GSK461364 | PLK1 | PLK | 0.0107 | uM | 7848.001 | 0.8084 | 0.2530 | 0.4548 | |
| HCC2185 | TNBC | Luminal | GSK461364 | PLK1 | PLK | 0.0533 | uM | 7848.001 | 0.5131 | -0.5389 | 0.4548 | |
| HCC2185 | TNBC | Luminal | GSK461364 | PLK1 | PLK | 0.267 | uM | 7848.001 | 0.5709 | -0.4167 | 0.4548 |