Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 184B5 | NM | Basal | GSK1838705A | IGF1R | RTK | 1.07 | uM | 5897.091 | 0.7360 | 0.5587 | 1.2296 | |
| 184B5 | NM | Basal | GSK1838705A | IGF1R | RTK | 5.33 | uM | 5897.091 | 0.5936 | 0.3086 | 1.2296 | |
| 184B5 | NM | Basal | GSK1838705A | IGF1R | RTK | 26.7 | uM | 5897.091 | 0.2444 | -0.3641 | 1.2296 | |
| 184B5 | NM | Basal | GSK1838705A | IGF1R | RTK | 133 | uM | 5897.091 | 0.0150 | -0.9343 | 1.2296 | |
| 600MPE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 5898.091 | 1.0031 | 1.0100 | 0.6159 | |
| 600MPE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 5898.091 | 0.9553 | 0.8570 | 0.6159 | |
| 600MPE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 5898.091 | 1.0111 | 1.0362 | 0.6159 | |
| 600MPE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0427 | uM | 5898.091 | 0.9895 | 0.9660 | 0.6159 | |
| 600MPE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.213 | uM | 5898.091 | 0.9358 | 0.7959 | 0.6159 | |
| 600MPE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 1.07 | uM | 5898.091 | 0.5355 | -0.2745 | 0.6159 | |
| 600MPE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 5.33 | uM | 5898.091 | 0.5705 | -0.1959 | 0.6159 | |
| 600MPE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 26.7 | uM | 5898.091 | 0.0149 | -0.9978 | 0.6159 | |
| 600MPE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 133 | uM | 5898.091 | 0.0212 | -0.9962 | 0.6159 | |
| 600MPE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 5899.07 | 1.0002 | 1.0005 | 0.8850 | |
| 600MPE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 5899.07 | 1.0036 | 1.0082 | 0.8850 | |
| 600MPE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 5899.07 | 0.9786 | 0.9518 | 0.8850 | |
| 600MPE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 5899.07 | 1.0168 | 1.0380 | 0.8850 | |
| 600MPE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.107 | uM | 5899.07 | 0.8415 | 0.6456 | 0.8850 | |
| 600MPE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.533 | uM | 5899.07 | 0.6294 | 0.1852 | 0.8850 | |
| 600MPE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 2.67 | uM | 5899.07 | 0.3140 | -0.4598 | 0.8850 | |
| 600MPE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 13.3 | uM | 5899.07 | 0.1046 | -0.8440 | 0.8850 | |
| 600MPE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 66.7 | uM | 5899.07 | 0.0306 | -0.9610 | 0.8850 | |
| 600MPE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 5899.09 | 0.9953 | 0.9910 | 1.0401 | |
| 600MPE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 5899.09 | 0.9608 | 0.9246 | 1.0401 | |
| 600MPE | HR+ | Luminal | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 5899.09 | 1.0105 | 1.0201 | 1.0401 |