Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM149PT | TNBC | Basal B | GSK1070916 | AURK | AURK | 6.67 | uM | 7917.001 | 0.3175 | 0.3554 | 2.9486 | |
| SUM149PT | TNBC | Basal B | GSK1070916 | AURK | AURK | 33.3 | uM | 7917.001 | 0.0089 | -0.5968 | 2.9486 | |
| SUM149PT | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.0000853 | uM | 9830.001 | 1.0955 | 1.0917 | 2.0346 | |
| SUM149PT | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.000427 | uM | 9830.001 | 1.0350 | 1.0341 | 2.0346 | |
| SUM149PT | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.00213 | uM | 9830.001 | 1.0760 | 1.0733 | 2.0346 | |
| SUM149PT | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.0107 | uM | 9830.001 | 0.9606 | 0.9609 | 2.0346 | |
| SUM149PT | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.0533 | uM | 9830.001 | 0.9954 | 0.9955 | 2.0346 | |
| SUM149PT | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.267 | uM | 9830.001 | 0.9772 | 0.9775 | 2.0346 | |
| SUM149PT | TNBC | Basal B | GSK1070916 | AURK | AURK | 1.33 | uM | 9830.001 | 0.9178 | 0.9175 | 2.0346 | |
| SUM149PT | TNBC | Basal B | GSK1070916 | AURK | AURK | 6.67 | uM | 9830.001 | 0.5273 | 0.4603 | 2.0346 | |
| SUM149PT | TNBC | Basal B | GSK1070916 | AURK | AURK | 33.3 | uM | 9830.001 | 0.0722 | -0.4504 | 2.0346 | |
| SUM159PT | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.0000853 | uM | 7918.001 | 1.0653 | 1.0444 | 2.8818 | |
| SUM159PT | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.000427 | uM | 7918.001 | 0.8979 | 0.9266 | 2.8818 | |
| SUM159PT | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.00213 | uM | 7918.001 | 1.1003 | 1.0674 | 2.8818 | |
| SUM159PT | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.0107 | uM | 7918.001 | 1.0204 | 1.0141 | 2.8818 | |
| SUM159PT | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.0533 | uM | 7918.001 | 0.8489 | 0.8895 | 2.8818 | |
| SUM159PT | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.267 | uM | 7918.001 | 0.8326 | 0.8768 | 2.8818 | |
| SUM159PT | TNBC | Basal B | GSK1070916 | AURK | AURK | 1.33 | uM | 7918.001 | 0.6646 | 0.7357 | 2.8818 | |
| SUM159PT | TNBC | Basal B | GSK1070916 | AURK | AURK | 6.67 | uM | 7918.001 | 0.3421 | 0.3784 | 2.8818 | |
| SUM159PT | TNBC | Basal B | GSK1070916 | AURK | AURK | 33.3 | uM | 7918.001 | 0.0131 | -0.5556 | 2.8818 | |
| SUM159PT | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.0000853 | uM | 7920.001 | 1.0995 | 1.0435 | 4.4085 | |
| SUM159PT | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.000427 | uM | 7920.001 | 0.9991 | 0.9996 | 4.4085 | |
| SUM159PT | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.00213 | uM | 7920.001 | 1.0565 | 1.0251 | 4.4085 | |
| SUM159PT | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.0107 | uM | 7920.001 | 1.0040 | 1.0018 | 4.4085 | |
| SUM159PT | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.0533 | uM | 7920.001 | 0.7324 | 0.8636 | 4.4085 |