Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM1315MO2 | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.0000853 | uM | 9797.001 | 1.0702 | 1.2391 | 0.6012 | |
| SUM1315MO2 | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.000427 | uM | 9797.001 | 1.0331 | 1.1112 | 0.6012 | |
| SUM1315MO2 | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.00213 | uM | 9797.001 | 1.0272 | 1.0914 | 0.6012 | |
| SUM1315MO2 | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.0107 | uM | 9797.001 | 0.9700 | 0.9013 | 0.6012 | |
| SUM1315MO2 | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.0533 | uM | 9797.001 | 1.0170 | 1.0567 | 0.6012 | |
| SUM1315MO2 | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.267 | uM | 9797.001 | 0.9615 | 0.8737 | 0.6012 | |
| SUM1315MO2 | TNBC | Basal B | GSK1070916 | AURK | AURK | 1.33 | uM | 9797.001 | 0.7721 | 0.3007 | 0.6012 | |
| SUM1315MO2 | TNBC | Basal B | GSK1070916 | AURK | AURK | 6.67 | uM | 9797.001 | 0.4012 | -0.5623 | 0.6012 | |
| SUM1315MO2 | TNBC | Basal B | GSK1070916 | AURK | AURK | 33.3 | uM | 9797.001 | 0.0739 | -0.9738 | 0.6012 | |
| SUM1315MO2 | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.0000853 | uM | 10139.001 | 1.0090 | 1.0245 | 0.7336 | |
| SUM1315MO2 | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.000427 | uM | 10139.001 | 1.0028 | 1.0076 | 0.7336 | |
| SUM1315MO2 | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.00213 | uM | 10139.001 | 1.0235 | 1.0643 | 0.7336 | |
| SUM1315MO2 | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.0107 | uM | 10139.001 | 0.9820 | 0.9511 | 0.7336 | |
| SUM1315MO2 | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.0533 | uM | 10139.001 | 0.9643 | 0.9033 | 0.7336 | |
| SUM1315MO2 | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.267 | uM | 10139.001 | 0.9309 | 0.8140 | 0.7336 | |
| SUM1315MO2 | TNBC | Basal B | GSK1070916 | AURK | AURK | 1.33 | uM | 10139.001 | 0.8373 | 0.5700 | 0.7336 | |
| SUM1315MO2 | TNBC | Basal B | GSK1070916 | AURK | AURK | 6.67 | uM | 10139.001 | 0.5598 | -0.0931 | 0.7336 | |
| SUM1315MO2 | TNBC | Basal B | GSK1070916 | AURK | AURK | 33.3 | uM | 10139.001 | 0.2272 | -0.7348 | 0.7336 | |
| SUM149PT | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.0000853 | uM | 7917.001 | 0.9429 | 0.9605 | 2.9486 | |
| SUM149PT | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.000427 | uM | 7917.001 | 0.9594 | 0.9721 | 2.9486 | |
| SUM149PT | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.00213 | uM | 7917.001 | 0.9623 | 0.9741 | 2.9486 | |
| SUM149PT | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.0107 | uM | 7917.001 | 0.8880 | 0.9210 | 2.9486 | |
| SUM149PT | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.0533 | uM | 7917.001 | 0.7835 | 0.8412 | 2.9486 | |
| SUM149PT | TNBC | Basal B | GSK1070916 | AURK | AURK | 0.267 | uM | 7917.001 | 0.7391 | 0.8051 | 2.9486 | |
| SUM149PT | TNBC | Basal B | GSK1070916 | AURK | AURK | 1.33 | uM | 7917.001 | 0.6593 | 0.7365 | 2.9486 |