Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 9258.011 | 0.5912 | -0.0576 | 0.6984 | |
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 144 | uM | 9258.011 | 0.6740 | 0.1368 | 0.6984 | |
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.000325 | uM | 9258.03 | 0.9624 | 0.8179 | 0.4015 | |
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.00162 | uM | 9258.03 | 1.0501 | 1.2591 | 0.4015 | |
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.00812 | uM | 9258.03 | 0.9620 | 0.8161 | 0.4015 | |
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.0406 | uM | 9258.03 | 0.9407 | 0.7174 | 0.4015 | |
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.203 | uM | 9258.03 | 0.7241 | -0.1051 | 0.4015 | |
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 1.01 | uM | 9258.03 | 0.8020 | 0.1545 | 0.4015 | |
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 5.07 | uM | 9258.03 | 0.6688 | -0.2655 | 0.4015 | |
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 25.4 | uM | 9258.03 | 0.6663 | -0.2725 | 0.4015 | |
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 127 | uM | 9258.03 | 0.5012 | -0.6420 | 0.4015 | |
| HCC1419 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 7819.075 | 0.9867 | 0.9509 | 0.5386 | |
| HCC1419 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00924 | uM | 7819.075 | 1.0769 | 1.2950 | 0.5386 | |
| HCC1419 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 7819.075 | 0.9998 | 0.9991 | 0.5386 | |
| HCC1419 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 7819.075 | 0.9038 | 0.6577 | 0.5386 | |
| HCC1419 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 7819.075 | 0.9398 | 0.7821 | 0.5386 | |
| HCC1419 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 7819.075 | 0.8871 | 0.6012 | 0.5386 | |
| HCC1419 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 7819.075 | 0.9645 | 0.8702 | 0.5386 | |
| HCC1419 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 144 | uM | 7819.075 | 0.8839 | 0.5906 | 0.5386 | |
| HCC1419 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 722 | uM | 7819.075 | 0.8850 | 0.5940 | 0.5386 | |
| HCC1419 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00037 | uM | 7820.011 | 1.0005 | 1.0016 | 0.6709 | |
| HCC1419 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 7820.011 | 0.9827 | 0.9486 | 0.6709 | |
| HCC1419 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00925 | uM | 7820.011 | 0.9862 | 0.9591 | 0.6709 | |
| HCC1419 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 7820.011 | 0.9512 | 0.8562 | 0.6709 | |
| HCC1419 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 7820.011 | 0.8512 | 0.5730 | 0.6709 |