Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1419 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 7820.011 | 0.8907 | 0.6831 | 0.6709 | |
| HCC1419 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 7820.011 | 0.8937 | 0.6915 | 0.6709 | |
| HCC1419 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 7820.011 | 0.9417 | 0.8286 | 0.6709 | |
| HCC1419 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 144 | uM | 7820.011 | 0.8897 | 0.6804 | 0.6709 | |
| HCC1419 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00037 | uM | 9278.011 | 1.0279 | 1.1039 | 0.5434 | |
| HCC1419 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 9278.011 | 0.9941 | 0.9782 | 0.5434 | |
| HCC1419 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00925 | uM | 9278.011 | 0.9458 | 0.8052 | 0.5434 | |
| HCC1419 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 9278.011 | 0.9013 | 0.6519 | 0.5434 | |
| HCC1419 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 9278.011 | 0.8704 | 0.5491 | 0.5434 | |
| HCC1419 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 9278.011 | 0.8027 | 0.3347 | 0.5434 | |
| HCC1419 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 9278.011 | 0.7820 | 0.2721 | 0.5434 | |
| HCC1419 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 9278.011 | 0.8625 | 0.5235 | 0.5434 | |
| HCC1419 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 144 | uM | 9278.011 | 0.8006 | 0.3284 | 0.5434 | |
| HCC1419 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.000168 | uM | 10019.12 | 0.9466 | 0.7881 | 0.4898 | |
| HCC1419 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00084 | uM | 10019.12 | 1.0315 | 1.1308 | 0.4898 | |
| HCC1419 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.0042 | uM | 10019.12 | 1.0115 | 1.0473 | 0.4898 | |
| HCC1419 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.021 | uM | 10019.12 | 1.0352 | 1.1462 | 0.4898 | |
| HCC1419 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.105 | uM | 10019.12 | 0.8937 | 0.5900 | 0.4898 | |
| HCC1419 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.525 | uM | 10019.12 | 0.9684 | 0.8732 | 0.4898 | |
| HCC1419 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 2.62 | uM | 10019.12 | 0.8386 | 0.3961 | 0.4898 | |
| HCC1419 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 13.1 | uM | 10019.12 | 0.8556 | 0.4546 | 0.4898 | |
| HCC1419 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 65.6 | uM | 10019.12 | 0.8898 | 0.5758 | 0.4898 | |
| HCC1428 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00037 | uM | 9294.011 | 0.9908 | 0.9747 | 0.7255 | |
| HCC1428 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 9294.011 | 0.9321 | 0.8153 | 0.7255 | |
| HCC1428 | HR+ | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00925 | uM | 9294.011 | 1.0184 | 1.0508 | 0.7255 |