Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.267 | uM | 9648.001 | 0.9730 | 0.9148 | 0.6289 | |
| MDA-MB-361 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 1.33 | uM | 9648.001 | 0.9253 | 0.7676 | 0.6289 | |
| MDA-MB-361 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 6.67 | uM | 9648.001 | 0.7597 | 0.2920 | 0.6289 | |
| MDA-MB-361 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 33.3 | uM | 9648.001 | 0.0956 | -0.9521 | 0.6289 | |
| MDA-MB-361 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0000853 | uM | 10095.001 | 0.9896 | 0.9771 | 0.9049 | |
| MDA-MB-361 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.000427 | uM | 10095.001 | 0.9541 | 0.8988 | 0.9049 | |
| MDA-MB-361 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.00213 | uM | 10095.001 | 0.9291 | 0.8439 | 0.9049 | |
| MDA-MB-361 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0107 | uM | 10095.001 | 0.9342 | 0.8551 | 0.9049 | |
| MDA-MB-361 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.0533 | uM | 10095.001 | 0.9679 | 0.9293 | 0.9049 | |
| MDA-MB-361 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 0.267 | uM | 10095.001 | 0.9842 | 0.9651 | 0.9049 | |
| MDA-MB-361 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 1.33 | uM | 10095.001 | 0.8725 | 0.7202 | 0.9049 | |
| MDA-MB-361 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 6.67 | uM | 10095.001 | 0.7251 | 0.4020 | 0.9049 | |
| MDA-MB-361 | HER2amp | Luminal | GSK1070916 | AURK | AURK | 33.3 | uM | 10095.001 | 0.0247 | -0.9666 | 0.9049 | |
| MDA-MB-415 | HR+ | Luminal | GSK1070916 | AURK | AURK | 0.0000853 | uM | 7897.001 | 1.0118 | 1.0316 | 0.7466 | |
| MDA-MB-415 | HR+ | Luminal | GSK1070916 | AURK | AURK | 0.000427 | uM | 7897.001 | 0.9294 | 0.8133 | 0.7466 | |
| MDA-MB-415 | HR+ | Luminal | GSK1070916 | AURK | AURK | 0.00213 | uM | 7897.001 | 0.9692 | 0.9180 | 0.7466 | |
| MDA-MB-415 | HR+ | Luminal | GSK1070916 | AURK | AURK | 0.0107 | uM | 7897.001 | 0.8516 | 0.6129 | 0.7466 | |
| MDA-MB-415 | HR+ | Luminal | GSK1070916 | AURK | AURK | 0.0533 | uM | 7897.001 | 0.8685 | 0.6559 | 0.7466 | |
| MDA-MB-415 | HR+ | Luminal | GSK1070916 | AURK | AURK | 0.267 | uM | 7897.001 | 0.8158 | 0.5228 | 0.7466 | |
| MDA-MB-415 | HR+ | Luminal | GSK1070916 | AURK | AURK | 1.33 | uM | 7897.001 | 0.7954 | 0.4719 | 0.7466 | |
| MDA-MB-415 | HR+ | Luminal | GSK1070916 | AURK | AURK | 6.67 | uM | 7897.001 | 0.5742 | -0.0488 | 0.7466 | |
| MDA-MB-415 | HR+ | Luminal | GSK1070916 | AURK | AURK | 33.3 | uM | 7897.001 | 0.0347 | -0.9778 | 0.7466 | |
| MDA-MB-415 | HR+ | Luminal | GSK1070916 | AURK | AURK | 0.0000853 | uM | 9664.001 | 0.9519 | 0.8803 | 0.7994 | |
| MDA-MB-415 | HR+ | Luminal | GSK1070916 | AURK | AURK | 0.000427 | uM | 9664.001 | 0.9607 | 0.9022 | 0.7994 | |
| MDA-MB-415 | HR+ | Luminal | GSK1070916 | AURK | AURK | 0.00213 | uM | 9664.001 | 0.9982 | 0.9954 | 0.7994 |