Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.00037 | uM | 7814.011 | 0.9601 | 0.9157 | 0.9472 | |
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 7814.011 | 0.9697 | 0.9361 | 0.9472 | |
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.00925 | uM | 7814.011 | 0.8834 | 0.7546 | 0.9472 | |
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 7814.011 | 0.7806 | 0.5397 | 0.9472 | |
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 7814.011 | 0.7528 | 0.4820 | 0.9472 | |
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 7814.011 | 0.6711 | 0.3126 | 0.9472 | |
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 7814.011 | 0.5818 | 0.1291 | 0.9472 | |
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 7814.011 | 0.5814 | 0.1281 | 0.9472 | |
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 144 | uM | 7814.011 | 0.5555 | 0.0751 | 0.9472 | |
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.000168 | uM | 9254.12 | 0.9699 | 0.9459 | 1.1139 | |
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.00084 | uM | 9254.12 | 1.0578 | 1.1036 | 1.1139 | |
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.0042 | uM | 9254.12 | 1.0769 | 1.1375 | 1.1139 | |
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.021 | uM | 9254.12 | 1.0121 | 1.0217 | 1.1139 | |
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.105 | uM | 9254.12 | 0.8858 | 0.7937 | 1.1139 | |
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.525 | uM | 9254.12 | 0.9042 | 0.8270 | 1.1139 | |
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 2.62 | uM | 9254.12 | 0.6999 | 0.4518 | 1.1139 | |
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 13.1 | uM | 9254.12 | 0.6569 | 0.3715 | 1.1139 | |
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 65.6 | uM | 9254.12 | 0.7979 | 0.6330 | 1.1139 | |
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.00037 | uM | 9258.011 | 0.9747 | 0.9278 | 0.6984 | |
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 9258.011 | 1.1129 | 1.3310 | 0.6984 | |
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.00925 | uM | 9258.011 | 1.0142 | 1.0408 | 0.6984 | |
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 9258.011 | 0.9509 | 0.8609 | 0.6984 | |
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 9258.011 | 0.8913 | 0.6961 | 0.6984 | |
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 9258.011 | 0.7698 | 0.3751 | 0.6984 | |
| HCC1395 | TNBC | Basal B | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 9258.011 | 0.6993 | 0.1985 | 0.6984 |