LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
Download: Excel (XLSX), Comma-separated (CSV)
Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|
MDA-MB-231 | PI103 | 0.37 | uM | LJP6 | 0.5356 | 0.0819 | 0.4198 | 0.1463 |
MDA-MB-231 | PI103 | 1.11 | uM | LJP6 | 0.4871 | 0.0380 | 0.3714 | 0.0717 |
MDA-MB-231 | PI103 | 3.33 | uM | LJP6 | 0.4373 | 0.0612 | 0.2914 | 0.1070 |
MDA-MB-231 | PI103 | 10 | uM | LJP6 | 0.3187 | 0.0498 | 0.0948 | 0.1051 |
MDA-MB-231 | Dovitinib | 0.04 | uM | LJP5 | 0.9094 | 0.0577 | 0.9028 | 0.0621 |
MDA-MB-231 | Dovitinib | 0.12 | uM | LJP5 | 0.8318 | 0.0704 | 0.8165 | 0.0783 |
MDA-MB-231 | Dovitinib | 0.37 | uM | LJP5 | 0.5990 | 0.0439 | 0.5336 | 0.0584 |
MDA-MB-231 | Dovitinib | 1.11 | uM | LJP5 | 0.5380 | 0.0484 | 0.4507 | 0.0688 |
MDA-MB-231 | Dovitinib | 3.33 | uM | LJP5 | 0.4614 | 0.0226 | 0.3427 | 0.0390 |
MDA-MB-231 | Dovitinib | 10 | uM | LJP5 | 0.3900 | 0.0312 | 0.2301 | 0.0569 |
MDA-MB-231 | GSK 690693 | 0.04 | uM | LJP5 | 0.8696 | 0.0470 | 0.8600 | 0.0511 |
MDA-MB-231 | GSK 690693 | 0.12 | uM | LJP5 | 0.9090 | 0.0113 | 0.9039 | 0.0121 |
MDA-MB-231 | GSK 690693 | 0.37 | uM | LJP5 | 0.9111 | 0.0120 | 0.9062 | 0.0120 |
MDA-MB-231 | GSK 690693 | 1.11 | uM | LJP5 | 0.9428 | 0.0148 | 0.9397 | 0.0151 |
MDA-MB-231 | GSK 690693 | 3.33 | uM | LJP5 | 1.0078 | 0.0178 | 1.0079 | 0.0183 |
MDA-MB-231 | GSK 690693 | 10 | uM | LJP5 | 0.8780 | 0.0401 | 0.8689 | 0.0460 |
MDA-MB-231 | SNS-032 | 0.04 | uM | LJP6 | 0.4478 | 0.0511 | 0.3143 | 0.0627 |
MDA-MB-231 | SNS-032 | 0.12 | uM | LJP6 | 0.1739 | 0.0306 | -0.2011 | 0.0950 |
MDA-MB-231 | SNS-032 | 0.37 | uM | LJP6 | 0.1582 | 0.0312 | -0.2404 | 0.0995 |
MDA-MB-231 | SNS-032 | 1.11 | uM | LJP6 | 0.1615 | 0.0265 | -0.2303 | 0.0878 |
MDA-MB-231 | SNS-032 | 3.33 | uM | LJP6 | 0.1738 | 0.0345 | -0.2031 | 0.1040 |
MDA-MB-231 | SNS-032 | 10 | uM | LJP6 | 0.1731 | 0.0250 | -0.2010 | 0.0815 |
MDA-MB-231 | Afatinib | 0.04 | uM | LJP6 | 0.8563 | 0.0734 | 0.8454 | 0.0779 |
MDA-MB-231 | Afatinib | 0.12 | uM | LJP6 | 0.8801 | 0.0281 | 0.8726 | 0.0271 |
MDA-MB-231 | Afatinib | 0.37 | uM | LJP6 | 0.7781 | 0.0208 | 0.7551 | 0.0234 |