LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Mean Relative Cell Count Standard Error of the Mean for Relative Cell Count Mean Normalized Growth Rate Inhibition Value Standard Error of the Mean for Normalized Growth Rate Inhibition Value
MDA-MB-231 PI103
0.37
uM
LJP6
0.5356 0.0819 0.4198 0.1463
MDA-MB-231 PI103
1.11
uM
LJP6
0.4871 0.0380 0.3714 0.0717
MDA-MB-231 PI103
3.33
uM
LJP6
0.4373 0.0612 0.2914 0.1070
MDA-MB-231 PI103
10
uM
LJP6
0.3187 0.0498 0.0948 0.1051
MDA-MB-231 Dovitinib
0.04
uM
LJP5
0.9094 0.0577 0.9028 0.0621
MDA-MB-231 Dovitinib
0.12
uM
LJP5
0.8318 0.0704 0.8165 0.0783
MDA-MB-231 Dovitinib
0.37
uM
LJP5
0.5990 0.0439 0.5336 0.0584
MDA-MB-231 Dovitinib
1.11
uM
LJP5
0.5380 0.0484 0.4507 0.0688
MDA-MB-231 Dovitinib
3.33
uM
LJP5
0.4614 0.0226 0.3427 0.0390
MDA-MB-231 Dovitinib
10
uM
LJP5
0.3900 0.0312 0.2301 0.0569
MDA-MB-231 GSK 690693
0.04
uM
LJP5
0.8696 0.0470 0.8600 0.0511
MDA-MB-231 GSK 690693
0.12
uM
LJP5
0.9090 0.0113 0.9039 0.0121
MDA-MB-231 GSK 690693
0.37
uM
LJP5
0.9111 0.0120 0.9062 0.0120
MDA-MB-231 GSK 690693
1.11
uM
LJP5
0.9428 0.0148 0.9397 0.0151
MDA-MB-231 GSK 690693
3.33
uM
LJP5
1.0078 0.0178 1.0079 0.0183
MDA-MB-231 GSK 690693
10
uM
LJP5
0.8780 0.0401 0.8689 0.0460
MDA-MB-231 SNS-032
0.04
uM
LJP6
0.4478 0.0511 0.3143 0.0627
MDA-MB-231 SNS-032
0.12
uM
LJP6
0.1739 0.0306 -0.2011 0.0950
MDA-MB-231 SNS-032
0.37
uM
LJP6
0.1582 0.0312 -0.2404 0.0995
MDA-MB-231 SNS-032
1.11
uM
LJP6
0.1615 0.0265 -0.2303 0.0878
MDA-MB-231 SNS-032
3.33
uM
LJP6
0.1738 0.0345 -0.2031 0.1040
MDA-MB-231 SNS-032
10
uM
LJP6
0.1731 0.0250 -0.2010 0.0815
MDA-MB-231 Afatinib
0.04
uM
LJP6
0.8563 0.0734 0.8454 0.0779
MDA-MB-231 Afatinib
0.12
uM
LJP6
0.8801 0.0281 0.8726 0.0271
MDA-MB-231 Afatinib
0.37
uM
LJP6
0.7781 0.0208 0.7551 0.0234