LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|
MDA-MB-231 | Afatinib | 1.11 | uM | LJP6 | 0.6861 | 0.0339 | 0.6410 | 0.0520 |
MDA-MB-231 | Afatinib | 3.33 | uM | LJP6 | 0.6028 | 0.0167 | 0.5368 | 0.0247 |
MDA-MB-231 | Afatinib | 10 | uM | LJP6 | 0.1707 | 0.0184 | -0.2053 | 0.0658 |
MDA-MB-231 | GSK1904529A | 0.04 | uM | LJP6 | 0.8272 | 0.0515 | 0.8131 | 0.0536 |
MDA-MB-231 | GSK1904529A | 0.12 | uM | LJP6 | 0.8724 | 0.0266 | 0.8637 | 0.0259 |
MDA-MB-231 | GSK1904529A | 0.37 | uM | LJP6 | 0.8985 | 0.0169 | 0.8926 | 0.0155 |
MDA-MB-231 | GSK1904529A | 1.11 | uM | LJP6 | 0.9066 | 0.0031 | 0.9004 | 0.0061 |
MDA-MB-231 | GSK1904529A | 3.33 | uM | LJP6 | 0.9717 | 0.0114 | 0.9705 | 0.0118 |
MDA-MB-231 | GSK1904529A | 10 | uM | LJP6 | 0.9424 | 0.0123 | 0.9394 | 0.0136 |
MDA-MB-231 | Linsitinib | 0.04 | uM | LJP5 | 0.8074 | 0.0249 | 0.7913 | 0.0274 |
MDA-MB-231 | Linsitinib | 0.12 | uM | LJP5 | 0.8543 | 0.0350 | 0.8434 | 0.0386 |
MDA-MB-231 | Linsitinib | 0.37 | uM | LJP5 | 0.8707 | 0.0444 | 0.8607 | 0.0492 |
MDA-MB-231 | Linsitinib | 1.11 | uM | LJP5 | 0.8723 | 0.0343 | 0.8619 | 0.0391 |
MDA-MB-231 | Linsitinib | 3.33 | uM | LJP5 | 0.8498 | 0.0421 | 0.8376 | 0.0467 |
MDA-MB-231 | Linsitinib | 10 | uM | LJP5 | 0.7283 | 0.0487 | 0.6973 | 0.0572 |
MDA-MB-231 | Ruxolitinib | 0.04 | uM | LJP5 | 0.9424 | 0.0353 | 0.9385 | 0.0377 |
MDA-MB-231 | Ruxolitinib | 0.12 | uM | LJP5 | 0.9285 | 0.0274 | 0.9224 | 0.0300 |
MDA-MB-231 | Ruxolitinib | 0.37 | uM | LJP5 | 0.9387 | 0.0467 | 0.9327 | 0.0503 |
MDA-MB-231 | Ruxolitinib | 1.11 | uM | LJP5 | 0.9537 | 0.0365 | 0.9496 | 0.0395 |
MDA-MB-231 | Ruxolitinib | 3.33 | uM | LJP5 | 0.9532 | 0.0225 | 0.9501 | 0.0249 |
MDA-MB-231 | Ruxolitinib | 10 | uM | LJP5 | 0.7189 | 0.1175 | 0.6729 | 0.1523 |
MDA-MB-231 | Momelotinib | 0.04 | uM | LJP5 | 0.8690 | 0.0312 | 0.8588 | 0.0339 |
MDA-MB-231 | Momelotinib | 0.12 | uM | LJP5 | 0.7972 | 0.0253 | 0.7772 | 0.0305 |
MDA-MB-231 | Momelotinib | 0.37 | uM | LJP5 | 0.7124 | 0.0384 | 0.6776 | 0.0504 |
MDA-MB-231 | Momelotinib | 1.11 | uM | LJP5 | 0.5979 | 0.0734 | 0.5274 | 0.1047 |