LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Mean Relative Cell Count Standard Error of the Mean for Relative Cell Count Mean Normalized Growth Rate Inhibition Value Standard Error of the Mean for Normalized Growth Rate Inhibition Value
MDA-MB-231 Afatinib
1.11
uM
LJP6
0.6861 0.0339 0.6410 0.0520
MDA-MB-231 Afatinib
3.33
uM
LJP6
0.6028 0.0167 0.5368 0.0247
MDA-MB-231 Afatinib
10
uM
LJP6
0.1707 0.0184 -0.2053 0.0658
MDA-MB-231 GSK1904529A
0.04
uM
LJP6
0.8272 0.0515 0.8131 0.0536
MDA-MB-231 GSK1904529A
0.12
uM
LJP6
0.8724 0.0266 0.8637 0.0259
MDA-MB-231 GSK1904529A
0.37
uM
LJP6
0.8985 0.0169 0.8926 0.0155
MDA-MB-231 GSK1904529A
1.11
uM
LJP6
0.9066 0.0031 0.9004 0.0061
MDA-MB-231 GSK1904529A
3.33
uM
LJP6
0.9717 0.0114 0.9705 0.0118
MDA-MB-231 GSK1904529A
10
uM
LJP6
0.9424 0.0123 0.9394 0.0136
MDA-MB-231 Linsitinib
0.04
uM
LJP5
0.8074 0.0249 0.7913 0.0274
MDA-MB-231 Linsitinib
0.12
uM
LJP5
0.8543 0.0350 0.8434 0.0386
MDA-MB-231 Linsitinib
0.37
uM
LJP5
0.8707 0.0444 0.8607 0.0492
MDA-MB-231 Linsitinib
1.11
uM
LJP5
0.8723 0.0343 0.8619 0.0391
MDA-MB-231 Linsitinib
3.33
uM
LJP5
0.8498 0.0421 0.8376 0.0467
MDA-MB-231 Linsitinib
10
uM
LJP5
0.7283 0.0487 0.6973 0.0572
MDA-MB-231 Ruxolitinib
0.04
uM
LJP5
0.9424 0.0353 0.9385 0.0377
MDA-MB-231 Ruxolitinib
0.12
uM
LJP5
0.9285 0.0274 0.9224 0.0300
MDA-MB-231 Ruxolitinib
0.37
uM
LJP5
0.9387 0.0467 0.9327 0.0503
MDA-MB-231 Ruxolitinib
1.11
uM
LJP5
0.9537 0.0365 0.9496 0.0395
MDA-MB-231 Ruxolitinib
3.33
uM
LJP5
0.9532 0.0225 0.9501 0.0249
MDA-MB-231 Ruxolitinib
10
uM
LJP5
0.7189 0.1175 0.6729 0.1523
MDA-MB-231 Momelotinib
0.04
uM
LJP5
0.8690 0.0312 0.8588 0.0339
MDA-MB-231 Momelotinib
0.12
uM
LJP5
0.7972 0.0253 0.7772 0.0305
MDA-MB-231 Momelotinib
0.37
uM
LJP5
0.7124 0.0384 0.6776 0.0504
MDA-MB-231 Momelotinib
1.11
uM
LJP5
0.5979 0.0734 0.5274 0.1047