LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | Momelotinib | 3.33 | uM | LJP5 | 0.4846 | 0.0994 | 0.3599 | 0.1603 |
| MDA-MB-231 | Momelotinib | 10 | uM | LJP5 | 0.2120 | 0.0459 | -0.1115 | 0.1129 |
| MDA-MB-231 | Fedratinib | 0.04 | uM | LJP5 | 1.0111 | 0.0414 | 1.0087 | 0.0426 |
| MDA-MB-231 | Fedratinib | 0.12 | uM | LJP5 | 0.9396 | 0.0397 | 0.9337 | 0.0434 |
| MDA-MB-231 | Fedratinib | 0.37 | uM | LJP5 | 0.8877 | 0.0547 | 0.8770 | 0.0634 |
| MDA-MB-231 | Fedratinib | 1.11 | uM | LJP5 | 0.6889 | 0.0875 | 0.6434 | 0.1094 |
| MDA-MB-231 | Fedratinib | 3.33 | uM | LJP5 | 0.3201 | 0.0605 | 0.1037 | 0.1088 |
| MDA-MB-231 | Fedratinib | 10 | uM | LJP5 | 0.1310 | 0.0281 | -0.3059 | 0.0846 |
| MDA-MB-231 | Trametinib | 0.04 | uM | LJP5 | 0.3075 | 0.0096 | 0.0906 | 0.0237 |
| MDA-MB-231 | Trametinib | 0.12 | uM | LJP5 | 0.3304 | 0.0301 | 0.1291 | 0.0598 |
| MDA-MB-231 | Trametinib | 0.37 | uM | LJP5 | 0.3230 | 0.0198 | 0.1175 | 0.0414 |
| MDA-MB-231 | Trametinib | 1.11 | uM | LJP5 | 0.3190 | 0.0197 | 0.1104 | 0.0415 |
| MDA-MB-231 | Trametinib | 3.33 | uM | LJP5 | 0.3192 | 0.0229 | 0.1104 | 0.0474 |
| MDA-MB-231 | Trametinib | 10 | uM | LJP5 | 0.3298 | 0.0311 | 0.1276 | 0.0612 |
| MDA-MB-231 | Omipalisib | 0.04 | uM | LJP6 | 0.5539 | 0.0504 | 0.4655 | 0.0830 |
| MDA-MB-231 | Omipalisib | 0.12 | uM | LJP6 | 0.4137 | 0.0345 | 0.2599 | 0.0709 |
| MDA-MB-231 | Omipalisib | 0.37 | uM | LJP6 | 0.3106 | 0.0282 | 0.0852 | 0.0711 |
| MDA-MB-231 | Omipalisib | 1.11 | uM | LJP6 | 0.2468 | 0.0233 | -0.0372 | 0.0664 |
| MDA-MB-231 | Omipalisib | 3.33 | uM | LJP6 | 0.2187 | 0.0352 | -0.0997 | 0.0921 |
| MDA-MB-231 | Omipalisib | 10 | uM | LJP6 | 0.1935 | 0.0492 | -0.1634 | 0.1256 |
| MDA-MB-231 | Buparlisib | 0.04 | uM | LJP5 | 1.0515 | 0.0373 | 1.0511 | 0.0364 |
| MDA-MB-231 | Buparlisib | 0.12 | uM | LJP5 | 0.9790 | 0.0143 | 0.9777 | 0.0154 |
| MDA-MB-231 | Buparlisib | 0.37 | uM | LJP5 | 0.8543 | 0.0209 | 0.8436 | 0.0228 |
| MDA-MB-231 | Buparlisib | 1.11 | uM | LJP5 | 0.5628 | 0.0304 | 0.4869 | 0.0361 |
| MDA-MB-231 | Buparlisib | 3.33 | uM | LJP5 | 0.3128 | 0.0129 | 0.0994 | 0.0299 |