LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | Buparlisib | 10 | uM | LJP5 | 0.1488 | 0.0247 | -0.2545 | 0.0709 |
| MDA-MB-231 | XL147 | 0.04 | uM | LJP5 | 1.0659 | 0.0239 | 1.0666 | 0.0238 |
| MDA-MB-231 | XL147 | 0.12 | uM | LJP5 | 1.0310 | 0.0406 | 1.0311 | 0.0415 |
| MDA-MB-231 | XL147 | 0.37 | uM | LJP5 | 1.0218 | 0.0350 | 1.0219 | 0.0358 |
| MDA-MB-231 | XL147 | 1.11 | uM | LJP5 | 1.0600 | 0.0390 | 1.0605 | 0.0391 |
| MDA-MB-231 | XL147 | 3.33 | uM | LJP5 | 1.0146 | 0.0324 | 1.0145 | 0.0331 |
| MDA-MB-231 | XL147 | 10 | uM | LJP5 | 0.9117 | 0.0320 | 0.9065 | 0.0345 |
| MDA-MB-231 | Y39983 | 0.04 | uM | LJP6 | 0.8871 | 0.0617 | 0.8731 | 0.0723 |
| MDA-MB-231 | Y39983 | 0.12 | uM | LJP6 | 0.8632 | 0.0505 | 0.8488 | 0.0600 |
| MDA-MB-231 | Y39983 | 0.37 | uM | LJP6 | 0.7998 | 0.0493 | 0.7766 | 0.0614 |
| MDA-MB-231 | Y39983 | 1.11 | uM | LJP6 | 0.7363 | 0.0390 | 0.7029 | 0.0497 |
| MDA-MB-231 | Y39983 | 3.33 | uM | LJP6 | 0.6413 | 0.0326 | 0.5864 | 0.0356 |
| MDA-MB-231 | Y39983 | 10 | uM | LJP6 | 0.1332 | 0.0212 | -0.3034 | 0.0807 |
| MDA-MB-231 | Nintedanib | 0.04 | uM | LJP6 | 1.0767 | 0.0149 | 1.0769 | 0.0166 |
| MDA-MB-231 | Nintedanib | 0.12 | uM | LJP6 | 1.0404 | 0.0106 | 1.0420 | 0.0127 |
| MDA-MB-231 | Nintedanib | 0.37 | uM | LJP6 | 0.9915 | 0.0050 | 0.9907 | 0.0053 |
| MDA-MB-231 | Nintedanib | 1.11 | uM | LJP6 | 0.9318 | 0.0382 | 0.9291 | 0.0388 |
| MDA-MB-231 | Nintedanib | 3.33 | uM | LJP6 | 0.8537 | 0.0774 | 0.8420 | 0.0832 |
| MDA-MB-231 | Nintedanib | 10 | uM | LJP6 | 0.4327 | 0.2196 | 0.2144 | 0.3218 |
| MDA-MB-231 | Foretinib | 0.04 | uM | LJP5 | 0.9149 | 0.0197 | 0.9102 | 0.0213 |
| MDA-MB-231 | Foretinib | 0.12 | uM | LJP5 | 0.6597 | 0.0041 | 0.6146 | 0.0067 |
| MDA-MB-231 | Foretinib | 0.37 | uM | LJP5 | 0.3534 | 0.0392 | 0.1678 | 0.0710 |
| MDA-MB-231 | Foretinib | 1.11 | uM | LJP5 | 0.3216 | 0.0356 | 0.1127 | 0.0662 |
| MDA-MB-231 | Foretinib | 3.33 | uM | LJP5 | 0.3028 | 0.0525 | 0.0741 | 0.0983 |
| MDA-MB-231 | Foretinib | 10 | uM | LJP5 | 0.1644 | 0.0111 | -0.2106 | 0.0325 |