LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Mean Relative Cell Count Standard Error of the Mean for Relative Cell Count Mean Normalized Growth Rate Inhibition Value Standard Error of the Mean for Normalized Growth Rate Inhibition Value
MCF 10A PD184352
0.37
uM
LJP5
0.3382 0.0681 0.4543 0.0338
MCF 10A PD184352
1.11
uM
LJP5
0.2807 0.0669 0.3713 0.0457
MCF 10A PD184352
3.33
uM
LJP5
0.2224 0.0567 0.2787 0.0391
MCF 10A PD184352
10
uM
LJP5
0.1663 0.0577 0.1650 0.0402
MCF 10A PLX-4720
0.04
uM
LJP5
0.9979 0.0198 0.9980 0.0111
MCF 10A PLX-4720
0.12
uM
LJP5
0.9895 0.0420 0.9903 0.0227
MCF 10A PLX-4720
0.37
uM
LJP5
0.9786 0.0564 0.9822 0.0310
MCF 10A PLX-4720
1.11
uM
LJP5
1.0103 0.0703 1.0017 0.0391
MCF 10A PLX-4720
3.33
uM
LJP5
1.0016 0.0595 1.0023 0.0379
MCF 10A PLX-4720
10
uM
LJP5
0.8229 0.0707 0.8964 0.0325
MCF 10A Lapatinib
0.04
uM
LJP6
0.9531 0.0346 0.9747 0.0165
MCF 10A Lapatinib
0.12
uM
LJP6
0.9242 0.0398 0.9566 0.0196
MCF 10A Lapatinib
0.37
uM
LJP6
0.9029 0.0512 0.9429 0.0269
MCF 10A Lapatinib
1.11
uM
LJP6
0.8254 0.0842 0.8946 0.0436
MCF 10A Lapatinib
3.33
uM
LJP6
0.6314 0.1438 0.7466 0.0931
MCF 10A Lapatinib
10
uM
LJP6
0.2413 0.0948 0.2883 0.1002
MCF 10A Sirolimus
0.04
uM
LJP6
0.9575 0.0677 0.9815 0.0428
MCF 10A Sirolimus
0.12
uM
LJP6
0.9913 0.0604 0.9991 0.0395
MCF 10A Sirolimus
0.37
uM
LJP6
0.9815 0.0726 0.9947 0.0474
MCF 10A Sirolimus
1.11
uM
LJP6
0.9860 0.0676 0.9972 0.0442
MCF 10A Sirolimus
3.33
uM
LJP6
0.9913 0.0787 0.9998 0.0516
MCF 10A Sirolimus
10
uM
LJP6
0.9675 0.0769 0.9860 0.0501
MCF 10A ZSTK474
0.04
uM
LJP6
0.9132 0.0753 0.9539 0.0376
MCF 10A ZSTK474
0.12
uM
LJP6
0.7457 0.1245 0.8421 0.0697
MCF 10A ZSTK474
0.37
uM
LJP6
0.5732 0.1383 0.6983 0.0921