LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|
MCF 10A | BI-2536 | 0.12 | uM | LJP6 | 0.0865 | 0.0042 | -0.0192 | 0.0802 |
MCF 10A | BI-2536 | 0.37 | uM | LJP6 | 0.0946 | 0.0059 | 0.0070 | 0.0747 |
MCF 10A | BI-2536 | 1.11 | uM | LJP6 | 0.0925 | 0.0102 | 0.0000 | 0.0614 |
MCF 10A | BI-2536 | 3.33 | uM | LJP6 | 0.0886 | 0.0117 | -0.0132 | 0.0568 |
MCF 10A | BI-2536 | 10 | uM | LJP6 | 0.0946 | 0.0162 | 0.0037 | 0.0473 |
MCF 10A | A443654 | 0.04 | uM | LJP6 | 0.7744 | 0.1985 | 0.8512 | 0.1263 |
MCF 10A | A443654 | 0.12 | uM | LJP6 | 0.5449 | 0.1759 | 0.6535 | 0.1428 |
MCF 10A | A443654 | 0.37 | uM | LJP6 | 0.1909 | 0.0826 | 0.2020 | 0.0834 |
MCF 10A | A443654 | 1.11 | uM | LJP6 | 0.1050 | 0.0525 | -0.0013 | 0.0666 |
MCF 10A | A443654 | 3.33 | uM | LJP6 | 0.0463 | 0.0147 | -0.1947 | 0.0575 |
MCF 10A | A443654 | 10 | uM | LJP6 | 0.0346 | 0.0095 | -0.2613 | 0.1071 |
MCF 10A | SB590885 | 0.04 | uM | LJP5 | 0.9665 | 0.0580 | 0.9770 | 0.0340 |
MCF 10A | SB590885 | 0.12 | uM | LJP5 | 0.9590 | 0.0575 | 0.9728 | 0.0342 |
MCF 10A | SB590885 | 0.37 | uM | LJP5 | 0.9745 | 0.0504 | 0.9834 | 0.0300 |
MCF 10A | SB590885 | 1.11 | uM | LJP5 | 0.9746 | 0.0296 | 0.9852 | 0.0180 |
MCF 10A | SB590885 | 3.33 | uM | LJP5 | 0.9349 | 0.0237 | 0.9640 | 0.0100 |
MCF 10A | SB590885 | 10 | uM | LJP5 | 0.5667 | 0.0905 | 0.6993 | 0.0424 |
MCF 10A | Pictilisib | 0.04 | uM | LJP6 | 0.7907 | 0.1530 | 0.8693 | 0.0890 |
MCF 10A | Pictilisib | 0.12 | uM | LJP6 | 0.6904 | 0.1656 | 0.7923 | 0.1069 |
MCF 10A | Pictilisib | 0.37 | uM | LJP6 | 0.5067 | 0.1499 | 0.6253 | 0.1187 |
MCF 10A | Pictilisib | 1.11 | uM | LJP6 | 0.3255 | 0.0981 | 0.4269 | 0.0834 |
MCF 10A | Pictilisib | 3.33 | uM | LJP6 | 0.2291 | 0.0643 | 0.2891 | 0.0500 |
MCF 10A | Pictilisib | 10 | uM | LJP6 | 0.1356 | 0.0445 | 0.1021 | 0.0219 |
MCF 10A | PD184352 | 0.04 | uM | LJP5 | 0.5260 | 0.0511 | 0.6612 | 0.0093 |
MCF 10A | PD184352 | 0.12 | uM | LJP5 | 0.4154 | 0.0681 | 0.5467 | 0.0334 |