LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Mean Relative Cell Count Standard Error of the Mean for Relative Cell Count Mean Normalized Growth Rate Inhibition Value Standard Error of the Mean for Normalized Growth Rate Inhibition Value
MCF 10A PF477736
10
uM
LJP5
 0.0854 0.0183 -0.0312 0.0355
MCF 10A LDN-193189
0.04
uM
LJP5
 1.0004 0.0153 0.9993 0.0081
MCF 10A LDN-193189
0.12
uM
LJP5
 0.9678 0.0071 0.9817 0.0019
MCF 10A LDN-193189
0.37
uM
LJP5
 0.9483 0.0123 0.9705 0.0044
MCF 10A LDN-193189
1.11
uM
LJP5
 0.9145 0.0419 0.9532 0.0184
MCF 10A LDN-193189
3.33
uM
LJP5
 0.5691 0.2071 0.6606 0.1962
MCF 10A LDN-193189
10
uM
LJP5
 0.0174 0.0045 -0.3955 0.0642
MCF 10A PF431396
0.04
uM
LJP5
 0.6248 0.0193 0.7436 0.0166
MCF 10A PF431396
0.12
uM
LJP5
 0.3747 0.0753 0.5012 0.0322
MCF 10A PF431396
0.37
uM
LJP5
 0.1990 0.0665 0.2335 0.0501
MCF 10A PF431396
1.11
uM
LJP5
 0.1353 0.0353 0.1057 0.0111
MCF 10A PF431396
3.33
uM
LJP5
 0.1159 0.0282 0.0578 0.0182
MCF 10A PF431396
10
uM
LJP5
 0.0536 0.0075 -0.1536 0.0942
MCF 10A Celastrol
0.04
uM
LJP6
 1.0779 0.0141 1.0426 0.0025
MCF 10A Celastrol
0.12
uM
LJP6
 1.0883 0.0268 1.0499 0.0161
MCF 10A Celastrol
0.37
uM
LJP6
 0.8560 0.1265 0.9215 0.0710
MCF 10A Celastrol
1.11
uM
LJP6
 0.2495 0.1768 0.2285 0.2141
MCF 10A Celastrol
3.33
uM
LJP6
 0.0380 0.0025 -0.2279 0.1107
MCF 10A Celastrol
10
uM
LJP6
 0.0617 0.0063 -0.1109 0.0706
MCF 10A SU11274
0.04
uM
LJP5
 1.0022 0.0171 1.0022 0.0110
MCF 10A SU11274
0.12
uM
LJP5
 0.9580 0.0191 0.9756 0.0114
MCF 10A SU11274
0.37
uM
LJP5
 0.9023 0.0189 0.9409 0.0115
MCF 10A SU11274
1.11
uM
LJP5
 0.7880 0.0172 0.8666 0.0057
MCF 10A SU11274
3.33
uM
LJP5
 0.6195 0.0442 0.7417 0.0127
MCF 10A SU11274
10
uM
LJP5
 0.3515 0.0629 0.4741 0.0185