LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
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MCF 10A | Canertinib | 0.04 | uM | LJP6 | 0.5927 | 0.1827 | 0.7024 | 0.1396 |
MCF 10A | Canertinib | 0.12 | uM | LJP6 | 0.4039 | 0.1493 | 0.4976 | 0.1512 |
MCF 10A | Canertinib | 0.37 | uM | LJP6 | 0.2596 | 0.0958 | 0.3126 | 0.1141 |
MCF 10A | Canertinib | 1.11 | uM | LJP6 | 0.1709 | 0.0550 | 0.1730 | 0.0603 |
MCF 10A | Canertinib | 3.33 | uM | LJP6 | 0.1354 | 0.0383 | 0.1050 | 0.0192 |
MCF 10A | Canertinib | 10 | uM | LJP6 | 0.0170 | 0.0034 | -0.3897 | 0.1288 |
MCF 10A | NVP-AEW541 | 0.04 | uM | LJP5 | 0.9758 | 0.0187 | 0.9876 | 0.0085 |
MCF 10A | NVP-AEW541 | 0.12 | uM | LJP5 | 0.9325 | 0.0410 | 0.9636 | 0.0187 |
MCF 10A | NVP-AEW541 | 0.37 | uM | LJP5 | 0.8135 | 0.1183 | 0.8874 | 0.0652 |
MCF 10A | NVP-AEW541 | 1.11 | uM | LJP5 | 0.6536 | 0.1689 | 0.7575 | 0.1145 |
MCF 10A | NVP-AEW541 | 3.33 | uM | LJP5 | 0.6339 | 0.1723 | 0.7408 | 0.1206 |
MCF 10A | NVP-AEW541 | 10 | uM | LJP5 | 0.3620 | 0.1267 | 0.4513 | 0.1317 |
MCF 10A | PHA-665752 | 0.04 | uM | LJP5 | 0.9834 | 0.0127 | 0.9915 | 0.0058 |
MCF 10A | PHA-665752 | 0.12 | uM | LJP5 | 0.9713 | 0.0017 | 0.9827 | 0.0026 |
MCF 10A | PHA-665752 | 0.37 | uM | LJP5 | 0.9585 | 0.0097 | 0.9763 | 0.0026 |
MCF 10A | PHA-665752 | 1.11 | uM | LJP5 | 0.9449 | 0.0116 | 0.9671 | 0.0068 |
MCF 10A | PHA-665752 | 3.33 | uM | LJP5 | 0.9410 | 0.0052 | 0.9647 | 0.0039 |
MCF 10A | PHA-665752 | 10 | uM | LJP5 | 0.4911 | 0.2262 | 0.5444 | 0.2468 |
MCF 10A | PI103 | 0.04 | uM | LJP6 | 0.9186 | 0.0719 | 0.9596 | 0.0382 |
MCF 10A | PI103 | 0.12 | uM | LJP6 | 0.6424 | 0.1919 | 0.7595 | 0.1276 |
MCF 10A | PI103 | 0.37 | uM | LJP6 | 0.3378 | 0.1553 | 0.4274 | 0.1373 |
MCF 10A | PI103 | 1.11 | uM | LJP6 | 0.1775 | 0.0574 | 0.1956 | 0.0388 |
MCF 10A | PI103 | 3.33 | uM | LJP6 | 0.1437 | 0.0441 | 0.1248 | 0.0186 |
MCF 10A | PI103 | 10 | uM | LJP6 | 0.1257 | 0.0375 | 0.0826 | 0.0192 |
MCF 10A | Dovitinib | 0.04 | uM | LJP5 | 0.9344 | 0.0359 | 0.9619 | 0.0184 |