LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|
MCF 10A | Saracatinib | 0.04 | uM | LJP6 | 1.0224 | 0.0096 | 1.0122 | 0.0041 |
MCF 10A | Saracatinib | 0.12 | uM | LJP6 | 0.9463 | 0.0111 | 0.9684 | 0.0040 |
MCF 10A | Saracatinib | 0.37 | uM | LJP6 | 0.8406 | 0.0589 | 0.9060 | 0.0260 |
MCF 10A | Saracatinib | 1.11 | uM | LJP6 | 0.6253 | 0.1162 | 0.7447 | 0.0698 |
MCF 10A | Saracatinib | 3.33 | uM | LJP6 | 0.4111 | 0.1084 | 0.5336 | 0.0825 |
MCF 10A | Saracatinib | 10 | uM | LJP6 | 0.1374 | 0.0436 | 0.1082 | 0.0189 |
MCF 10A | Sigma A6730 | 0.04 | uM | LJP5 | 0.9873 | 0.0125 | 0.9935 | 0.0059 |
MCF 10A | Sigma A6730 | 0.12 | uM | LJP5 | 0.9628 | 0.0146 | 0.9791 | 0.0059 |
MCF 10A | Sigma A6730 | 0.37 | uM | LJP5 | 0.9501 | 0.0155 | 0.9722 | 0.0053 |
MCF 10A | Sigma A6730 | 1.11 | uM | LJP5 | 0.8622 | 0.0609 | 0.9216 | 0.0276 |
MCF 10A | Sigma A6730 | 3.33 | uM | LJP5 | 0.8993 | 0.0551 | 0.9453 | 0.0272 |
MCF 10A | Sigma A6730 | 10 | uM | LJP5 | 0.4793 | 0.1235 | 0.6053 | 0.0889 |
MCF 10A | WH-4-025 | 0.04 | uM | LJP5 | 1.0094 | 0.0319 | 1.0061 | 0.0201 |
MCF 10A | WH-4-025 | 0.12 | uM | LJP5 | 0.8237 | 0.0735 | 0.8960 | 0.0343 |
MCF 10A | WH-4-025 | 0.37 | uM | LJP5 | 0.6940 | 0.0918 | 0.8040 | 0.0445 |
MCF 10A | WH-4-025 | 1.11 | uM | LJP5 | 0.3831 | 0.1024 | 0.4996 | 0.0764 |
MCF 10A | WH-4-025 | 3.33 | uM | LJP5 | 0.2470 | 0.0806 | 0.3113 | 0.0611 |
MCF 10A | WH-4-025 | 10 | uM | LJP5 | 0.1874 | 0.0600 | 0.2092 | 0.0408 |
MCF 10A | R406 | 0.04 | uM | LJP6 | 0.9536 | 0.0416 | 0.9781 | 0.0225 |
MCF 10A | R406 | 0.12 | uM | LJP6 | 0.9384 | 0.0345 | 0.9668 | 0.0199 |
MCF 10A | R406 | 0.37 | uM | LJP6 | 0.9000 | 0.0453 | 0.9448 | 0.0233 |
MCF 10A | R406 | 1.11 | uM | LJP6 | 0.8317 | 0.0795 | 0.9036 | 0.0396 |
MCF 10A | R406 | 3.33 | uM | LJP6 | 0.7145 | 0.1157 | 0.8212 | 0.0635 |
MCF 10A | R406 | 10 | uM | LJP6 | 0.5367 | 0.1311 | 0.6686 | 0.0828 |
MCF 10A | BI-2536 | 0.04 | uM | LJP6 | 0.0782 | 0.0062 | -0.0473 | 0.0749 |