LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|
MCF 10A | CGP60474 | 10 | uM | LJP6 | 0.0345 | 0.0042 | -0.2517 | 0.0988 |
MCF 10A | PD173074 | 0.04 | uM | LJP6 | 1.0379 | 0.0026 | 1.0217 | 0.0018 |
MCF 10A | PD173074 | 0.12 | uM | LJP6 | 1.0089 | 0.0015 | 1.0053 | 0.0014 |
MCF 10A | PD173074 | 0.37 | uM | LJP6 | 0.9979 | 0.0036 | 0.9981 | 0.0022 |
MCF 10A | PD173074 | 1.11 | uM | LJP6 | 0.9898 | 0.0063 | 0.9929 | 0.0046 |
MCF 10A | PD173074 | 3.33 | uM | LJP6 | 0.9771 | 0.0150 | 0.9845 | 0.0093 |
MCF 10A | PD173074 | 10 | uM | LJP6 | 0.5172 | 0.1188 | 0.6440 | 0.0840 |
MCF 10A | Crizotinib | 0.04 | uM | LJP5 | 0.9774 | 0.0243 | 0.9881 | 0.0121 |
MCF 10A | Crizotinib | 0.12 | uM | LJP5 | 0.9354 | 0.0381 | 0.9636 | 0.0183 |
MCF 10A | Crizotinib | 0.37 | uM | LJP5 | 0.8891 | 0.0279 | 0.9340 | 0.0126 |
MCF 10A | Crizotinib | 1.11 | uM | LJP5 | 0.8438 | 0.0317 | 0.9063 | 0.0087 |
MCF 10A | Crizotinib | 3.33 | uM | LJP5 | 0.7358 | 0.0519 | 0.8331 | 0.0160 |
MCF 10A | Crizotinib | 10 | uM | LJP5 | 0.1311 | 0.0341 | 0.0940 | 0.0096 |
MCF 10A | BMS345541 | 0.04 | uM | LJP6 | 0.9965 | 0.0125 | 0.9964 | 0.0066 |
MCF 10A | BMS345541 | 0.12 | uM | LJP6 | 0.9670 | 0.0108 | 0.9787 | 0.0082 |
MCF 10A | BMS345541 | 0.37 | uM | LJP6 | 0.9594 | 0.0088 | 0.9742 | 0.0091 |
MCF 10A | BMS345541 | 1.11 | uM | LJP6 | 0.9481 | 0.0106 | 0.9670 | 0.0112 |
MCF 10A | BMS345541 | 3.33 | uM | LJP6 | 0.9288 | 0.0143 | 0.9570 | 0.0102 |
MCF 10A | BMS345541 | 10 | uM | LJP6 | 0.7622 | 0.0575 | 0.8502 | 0.0264 |
MCF 10A | KIN001-043 | 0.04 | uM | LJP6 | 1.0015 | 0.0369 | 0.9981 | 0.0195 |
MCF 10A | KIN001-043 | 0.12 | uM | LJP6 | 0.9693 | 0.0295 | 0.9803 | 0.0170 |
MCF 10A | KIN001-043 | 0.37 | uM | LJP6 | 0.9572 | 0.0166 | 0.9749 | 0.0098 |
MCF 10A | KIN001-043 | 1.11 | uM | LJP6 | 0.9024 | 0.0435 | 0.9462 | 0.0191 |
MCF 10A | KIN001-043 | 3.33 | uM | LJP6 | 0.7613 | 0.0928 | 0.8549 | 0.0461 |
MCF 10A | KIN001-043 | 10 | uM | LJP6 | 0.3763 | 0.0981 | 0.4937 | 0.0755 |