LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Mean Relative Cell Count Standard Error of the Mean for Relative Cell Count Mean Normalized Growth Rate Inhibition Value Standard Error of the Mean for Normalized Growth Rate Inhibition Value
MCF 10A ZSTK474
1.11
uM
LJP6
0.3514 0.0859 0.4716 0.0482
MCF 10A ZSTK474
3.33
uM
LJP6
0.2295 0.0610 0.2958 0.0280
MCF 10A ZSTK474
10
uM
LJP6
0.1661 0.0412 0.1788 0.0397
MCF 10A BX-912
0.04
uM
LJP5
0.9161 0.0097 0.9500 0.0013
MCF 10A BX-912
0.12
uM
LJP5
0.8705 0.0545 0.9197 0.0355
MCF 10A BX-912
0.37
uM
LJP5
0.5533 0.1711 0.6478 0.1740
MCF 10A BX-912
1.11
uM
LJP5
0.1782 0.0263 0.2062 0.0388
MCF 10A BX-912
3.33
uM
LJP5
0.1613 0.0219 0.1719 0.0392
MCF 10A BX-912
10
uM
LJP5
0.1264 0.0255 0.0883 0.0331
MCF 10A Selumetinib
0.04
uM
LJP6
0.4593 0.0618 0.5980 0.0148
MCF 10A Selumetinib
0.12
uM
LJP6
0.3366 0.0658 0.4552 0.0304
MCF 10A Selumetinib
0.37
uM
LJP6
0.2690 0.0583 0.3597 0.0326
MCF 10A Selumetinib
1.11
uM
LJP6
0.2217 0.0558 0.2814 0.0306
MCF 10A Selumetinib
3.33
uM
LJP6
0.2034 0.0526 0.2497 0.0234
MCF 10A Selumetinib
10
uM
LJP6
0.1680 0.0505 0.1772 0.0242
MCF 10A MK2206
0.04
uM
LJP6
0.9802 0.0352 0.9896 0.0219
MCF 10A MK2206
0.12
uM
LJP6
0.9487 0.0346 0.9723 0.0210
MCF 10A MK2206
0.37
uM
LJP6
0.5985 0.1758 0.7046 0.1277
MCF 10A MK2206
1.11
uM
LJP6
0.8134 0.0765 0.8916 0.0389
MCF 10A MK2206
3.33
uM
LJP6
0.7300 0.0931 0.8333 0.0472
MCF 10A MK2206
10
uM
LJP6
0.3186 0.0862 0.4290 0.0521
MCF 10A AZD-6482
0.04
uM
LJP5
0.9843 0.0223 0.9935 0.0112
MCF 10A AZD-6482
0.12
uM
LJP5
0.9117 0.0658 0.9524 0.0322
MCF 10A AZD-6482
0.37
uM
LJP5
0.8888 0.0663 0.9376 0.0320
MCF 10A AZD-6482
1.11
uM
LJP5
0.8190 0.1029 0.8911 0.0545