LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|
MCF 10A | ZSTK474 | 1.11 | uM | LJP6 | 0.3514 | 0.0859 | 0.4716 | 0.0482 |
MCF 10A | ZSTK474 | 3.33 | uM | LJP6 | 0.2295 | 0.0610 | 0.2958 | 0.0280 |
MCF 10A | ZSTK474 | 10 | uM | LJP6 | 0.1661 | 0.0412 | 0.1788 | 0.0397 |
MCF 10A | BX-912 | 0.04 | uM | LJP5 | 0.9161 | 0.0097 | 0.9500 | 0.0013 |
MCF 10A | BX-912 | 0.12 | uM | LJP5 | 0.8705 | 0.0545 | 0.9197 | 0.0355 |
MCF 10A | BX-912 | 0.37 | uM | LJP5 | 0.5533 | 0.1711 | 0.6478 | 0.1740 |
MCF 10A | BX-912 | 1.11 | uM | LJP5 | 0.1782 | 0.0263 | 0.2062 | 0.0388 |
MCF 10A | BX-912 | 3.33 | uM | LJP5 | 0.1613 | 0.0219 | 0.1719 | 0.0392 |
MCF 10A | BX-912 | 10 | uM | LJP5 | 0.1264 | 0.0255 | 0.0883 | 0.0331 |
MCF 10A | Selumetinib | 0.04 | uM | LJP6 | 0.4593 | 0.0618 | 0.5980 | 0.0148 |
MCF 10A | Selumetinib | 0.12 | uM | LJP6 | 0.3366 | 0.0658 | 0.4552 | 0.0304 |
MCF 10A | Selumetinib | 0.37 | uM | LJP6 | 0.2690 | 0.0583 | 0.3597 | 0.0326 |
MCF 10A | Selumetinib | 1.11 | uM | LJP6 | 0.2217 | 0.0558 | 0.2814 | 0.0306 |
MCF 10A | Selumetinib | 3.33 | uM | LJP6 | 0.2034 | 0.0526 | 0.2497 | 0.0234 |
MCF 10A | Selumetinib | 10 | uM | LJP6 | 0.1680 | 0.0505 | 0.1772 | 0.0242 |
MCF 10A | MK2206 | 0.04 | uM | LJP6 | 0.9802 | 0.0352 | 0.9896 | 0.0219 |
MCF 10A | MK2206 | 0.12 | uM | LJP6 | 0.9487 | 0.0346 | 0.9723 | 0.0210 |
MCF 10A | MK2206 | 0.37 | uM | LJP6 | 0.5985 | 0.1758 | 0.7046 | 0.1277 |
MCF 10A | MK2206 | 1.11 | uM | LJP6 | 0.8134 | 0.0765 | 0.8916 | 0.0389 |
MCF 10A | MK2206 | 3.33 | uM | LJP6 | 0.7300 | 0.0931 | 0.8333 | 0.0472 |
MCF 10A | MK2206 | 10 | uM | LJP6 | 0.3186 | 0.0862 | 0.4290 | 0.0521 |
MCF 10A | AZD-6482 | 0.04 | uM | LJP5 | 0.9843 | 0.0223 | 0.9935 | 0.0112 |
MCF 10A | AZD-6482 | 0.12 | uM | LJP5 | 0.9117 | 0.0658 | 0.9524 | 0.0322 |
MCF 10A | AZD-6482 | 0.37 | uM | LJP5 | 0.8888 | 0.0663 | 0.9376 | 0.0320 |
MCF 10A | AZD-6482 | 1.11 | uM | LJP5 | 0.8190 | 0.1029 | 0.8911 | 0.0545 |