LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Mean Relative Cell Count Standard Error of the Mean for Relative Cell Count Mean Normalized Growth Rate Inhibition Value Standard Error of the Mean for Normalized Growth Rate Inhibition Value
Hs 578T Dactolisib
3.33
uM
LJP5
0.2917 0.0370 0.1152 0.0302
Hs 578T Dactolisib
10
uM
LJP5
0.2986 0.0349 0.1280 0.0253
Hs 578T Alpelisib
0.04
uM
LJP5
0.9700 0.0064 0.9710 0.0068
Hs 578T Alpelisib
0.12
uM
LJP5
0.9115 0.0090 0.9151 0.0006
Hs 578T Alpelisib
0.37
uM
LJP5
0.8671 0.0186 0.8707 0.0150
Hs 578T Alpelisib
1.11
uM
LJP5
0.8344 0.0234 0.8380 0.0152
Hs 578T Alpelisib
3.33
uM
LJP5
0.7641 0.0163 0.7619 0.0067
Hs 578T Alpelisib
10
uM
LJP5
0.5914 0.0310 0.5605 0.0295
Hs 578T GDC-0980
0.04
uM
LJP5
0.6791 0.0462 0.6701 0.0206
Hs 578T GDC-0980
0.12
uM
LJP5
0.4870 0.0327 0.4240 0.0231
Hs 578T GDC-0980
0.37
uM
LJP5
0.3803 0.0341 0.2650 0.0441
Hs 578T GDC-0980
1.11
uM
LJP5
0.3342 0.0409 0.1883 0.0593
Hs 578T GDC-0980
3.33
uM
LJP5
0.3159 0.0455 0.1561 0.0658
Hs 578T GDC-0980
10
uM
LJP5
0.2897 0.0417 0.1088 0.0677
Hs 578T Mitoxantrone
0.04
uM
LJP5
0.2816 0.0639 0.0910 0.0551
Hs 578T Mitoxantrone
0.04
uM
LJP6
0.2781 0.0733 0.0713 0.0767
Hs 578T Mitoxantrone
0.12
uM
LJP5
0.2320 0.0449 -0.0038 0.0281
Hs 578T Mitoxantrone
0.12
uM
LJP6
0.2229 0.0384 -0.0308 0.0208
Hs 578T Mitoxantrone
0.37
uM
LJP5
0.2044 0.0474 -0.0655 0.0346
Hs 578T Mitoxantrone
0.37
uM
LJP6
0.2111 0.0392 -0.0569 0.0180
Hs 578T Mitoxantrone
1.11
uM
LJP5
0.1506 0.0489 -0.2049 0.0561
Hs 578T Mitoxantrone
1.11
uM
LJP6
0.1523 0.0479 -0.2085 0.0559
Hs 578T Mitoxantrone
3.33
uM
LJP5
0.0878 0.0385 -0.3978 0.0677
Hs 578T Mitoxantrone
3.33
uM
LJP6
0.0930 0.0400 -0.3911 0.0688
Hs 578T Mitoxantrone
10
uM
LJP5
0.0659 0.0380 -0.5259 0.1101