LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Tozasertib | 3.33 | uM | LJP5 | 72 | hr | 1209 | 1426 | 4203 | 0.3400 | 0.0963 |
| MCF7 | Tozasertib | 10 | uM | LJP5 | 72 | hr | 1209 | 1281 | 4203 | 0.3056 | 0.0327 |
| MCF7 | Imatinib | 0.04 | uM | LJP6 | 72 | hr | 1209 | 3887 | 4012 | 0.9694 | 0.9648 |
| MCF7 | Imatinib | 0.12 | uM | LJP6 | 72 | hr | 1209 | 3944 | 4012 | 0.9830 | 0.9802 |
| MCF7 | Imatinib | 0.37 | uM | LJP6 | 72 | hr | 1209 | 4055 | 4012 | 1.0095 | 1.0095 |
| MCF7 | Imatinib | 1.11 | uM | LJP6 | 72 | hr | 1209 | 3996 | 4012 | 0.9977 | 0.9984 |
| MCF7 | Imatinib | 3.33 | uM | LJP6 | 72 | hr | 1209 | 3840 | 4012 | 0.9565 | 0.9487 |
| MCF7 | Imatinib | 10 | uM | LJP6 | 72 | hr | 1209 | 3530 | 4012 | 0.8798 | 0.8571 |
| MCF7 | NVP-TAE684 | 0.04 | uM | LJP6 | 72 | hr | 1209 | 1984 | 4012 | 0.4944 | 0.3304 |
| MCF7 | NVP-TAE684 | 0.12 | uM | LJP6 | 72 | hr | 1209 | 1297 | 4012 | 0.3227 | 0.0386 |
| MCF7 | NVP-TAE684 | 0.37 | uM | LJP6 | 72 | hr | 1209 | 964 | 4012 | 0.2401 | -0.1248 |
| MCF7 | NVP-TAE684 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 878 | 4012 | 0.2191 | -0.1695 |
| MCF7 | NVP-TAE684 | 3.33 | uM | LJP6 | 72 | hr | 1209 | 945 | 4012 | 0.2362 | -0.1332 |
| MCF7 | NVP-TAE684 | 10 | uM | LJP6 | 72 | hr | 1209 | 508 | 4012 | 0.1267 | -0.3945 |
| MCF7 | CGP60474 | 0.04 | uM | LJP5 | 72 | hr | 1209 | 3388 | 4203 | 0.8081 | 0.7768 |
| MCF7 | CGP60474 | 0.04 | uM | LJP6 | 72 | hr | 1209 | 681 | 4012 | 0.1703 | -0.2823 |
| MCF7 | CGP60474 | 0.12 | uM | LJP5 | 72 | hr | 1209 | 668 | 4203 | 0.1593 | -0.2814 |
| MCF7 | CGP60474 | 0.12 | uM | LJP6 | 72 | hr | 1209 | 712 | 4012 | 0.1776 | -0.2642 |
| MCF7 | CGP60474 | 0.37 | uM | LJP5 | 72 | hr | 1209 | 566 | 4203 | 0.1350 | -0.3455 |
| MCF7 | CGP60474 | 0.37 | uM | LJP6 | 72 | hr | 1209 | 782 | 4012 | 0.1951 | -0.2230 |
| MCF7 | CGP60474 | 1.11 | uM | LJP5 | 72 | hr | 1209 | 591 | 4203 | 0.1408 | -0.3292 |
| MCF7 | CGP60474 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 672 | 4012 | 0.1679 | -0.2884 |
| MCF7 | CGP60474 | 3.33 | uM | LJP5 | 72 | hr | 1209 | 642 | 4203 | 0.1534 | -0.2971 |
| MCF7 | CGP60474 | 3.33 | uM | LJP6 | 72 | hr | 1209 | 707 | 4012 | 0.1766 | -0.2676 |
| MCF7 | CGP60474 | 10 | uM | LJP5 | 72 | hr | 1209 | 568 | 4203 | 0.1357 | -0.3435 |