LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 XMD11-85h
0.37
uM
LJP6
 72
hr
 1209 3735 4012 0.9340 0.9227
MCF7 XMD11-85h
1.11
uM
LJP6
 72
hr
 1209 3420 4012 0.8521 0.8228
MCF7 XMD11-85h
3.33
uM
LJP6
 72
hr
 1209 3452 4012 0.8600 0.8325
MCF7 XMD11-85h
10
uM
LJP6
 72
hr
 1209 1830 4012 0.4564 0.2705
MCF7 XMD16-144
0.04
uM
LJP5
 72
hr
 1209 1543 4203 0.3684 0.1458
MCF7 XMD16-144
0.12
uM
LJP5
 72
hr
 1209 1550 4203 0.3694 0.1482
MCF7 XMD16-144
0.37
uM
LJP5
 72
hr
 1209 1495 4203 0.3560 0.1244
MCF7 XMD16-144
1.11
uM
LJP5
 72
hr
 1209 1515 4203 0.3611 0.1337
MCF7 XMD16-144
3.33
uM
LJP5
 72
hr
 1209 1457 4203 0.3477 0.1100
MCF7 XMD16-144
10
uM
LJP5
 72
hr
 1209 685 4203 0.1634 -0.2713
MCF7 Erlotinib
0.04
uM
LJP5
 72
hr
 1209 3874 4203 0.9233 0.9139
MCF7 Erlotinib
0.12
uM
LJP5
 72
hr
 1209 3863 4203 0.9189 0.9076
MCF7 Erlotinib
0.37
uM
LJP5
 72
hr
 1209 4208 4203 1.0017 1.0023
MCF7 Erlotinib
1.11
uM
LJP5
 72
hr
 1209 4308 4203 1.0255 1.0285
MCF7 Erlotinib
3.33
uM
LJP5
 72
hr
 1209 4251 4203 1.0131 1.0156
MCF7 Erlotinib
10
uM
LJP5
 72
hr
 1209 3651 4203 0.8706 0.8516
MCF7 Gefitinib
0.04
uM
LJP6
 72
hr
 1209 4112 4012 1.0253 1.0295
MCF7 Gefitinib
0.12
uM
LJP6
 72
hr
 1209 3983 4012 0.9927 0.9912
MCF7 Gefitinib
0.37
uM
LJP6
 72
hr
 1209 3898 4012 0.9712 0.9657
MCF7 Gefitinib
1.11
uM
LJP6
 72
hr
 1209 4054 4012 1.0093 1.0094
MCF7 Gefitinib
3.33
uM
LJP6
 72
hr
 1209 3922 4012 0.9767 0.9717
MCF7 Gefitinib
10
uM
LJP6
 72
hr
 1209 3232 4012 0.8057 0.7652
MCF7 Nilotinib
0.04
uM
LJP5
 72
hr
 1209 4224 4203 1.0061 1.0075
MCF7 Nilotinib
0.12
uM
LJP5
 72
hr
 1209 4205 4203 0.9983 0.9950
MCF7 Nilotinib
0.37
uM
LJP5
 72
hr
 1209 4013 4203 0.9567 0.9522