LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Nilotinib | 1.11 | uM | LJP5 | 72 | hr | 1209 | 3988 | 4203 | 0.9487 | 0.9418 |
| MCF7 | Nilotinib | 3.33 | uM | LJP5 | 72 | hr | 1209 | 3829 | 4203 | 0.9125 | 0.9014 |
| MCF7 | Nilotinib | 10 | uM | LJP5 | 72 | hr | 1209 | 957 | 4203 | 0.2280 | -0.1225 |
| MCF7 | JNK-9L | 0.04 | uM | LJP6 | 72 | hr | 1209 | 3341 | 4012 | 0.8321 | 0.7973 |
| MCF7 | JNK-9L | 0.12 | uM | LJP6 | 72 | hr | 1209 | 3099 | 4012 | 0.7703 | 0.7159 |
| MCF7 | JNK-9L | 0.37 | uM | LJP6 | 72 | hr | 1209 | 1504 | 4012 | 0.3745 | 0.1325 |
| MCF7 | JNK-9L | 1.11 | uM | LJP6 | 72 | hr | 1209 | 460 | 4012 | 0.1147 | -0.4285 |
| MCF7 | JNK-9L | 3.33 | uM | LJP6 | 72 | hr | 1209 | 353 | 4012 | 0.0879 | -0.5100 |
| MCF7 | JNK-9L | 10 | uM | LJP6 | 72 | hr | 1209 | 233 | 4012 | 0.0581 | -0.6146 |
| MCF7 | PD0325901 | 0.04 | uM | LJP5 | 72 | hr | 1209 | 2624 | 4203 | 0.6249 | 0.5392 |
| MCF7 | PD0325901 | 0.04 | uM | LJP6 | 72 | hr | 1209 | 2638 | 4012 | 0.6588 | 0.5713 |
| MCF7 | PD0325901 | 0.12 | uM | LJP5 | 72 | hr | 1209 | 2623 | 4203 | 0.6261 | 0.5410 |
| MCF7 | PD0325901 | 0.12 | uM | LJP6 | 72 | hr | 1209 | 2557 | 4012 | 0.6382 | 0.5427 |
| MCF7 | PD0325901 | 0.37 | uM | LJP5 | 72 | hr | 1209 | 2390 | 4203 | 0.5695 | 0.4617 |
| MCF7 | PD0325901 | 0.37 | uM | LJP6 | 72 | hr | 1209 | 2523 | 4012 | 0.6294 | 0.5301 |
| MCF7 | PD0325901 | 1.11 | uM | LJP5 | 72 | hr | 1209 | 2197 | 4203 | 0.5232 | 0.3938 |
| MCF7 | PD0325901 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 2208 | 4012 | 0.5513 | 0.4172 |
| MCF7 | PD0325901 | 3.33 | uM | LJP5 | 72 | hr | 1209 | 1945 | 4203 | 0.4620 | 0.2995 |
| MCF7 | PD0325901 | 3.33 | uM | LJP6 | 72 | hr | 1209 | 1875 | 4012 | 0.4666 | 0.2854 |
| MCF7 | PD0325901 | 10 | uM | LJP5 | 72 | hr | 1209 | 1625 | 4203 | 0.3858 | 0.1753 |
| MCF7 | PD0325901 | 10 | uM | LJP6 | 72 | hr | 1209 | 1471 | 4012 | 0.3650 | 0.1127 |
| MCF7 | Geldanamycin | 0.04 | uM | LJP5 | 72 | hr | 1209 | 2534 | 4203 | 0.6017 | 0.5052 |
| MCF7 | Geldanamycin | 0.04 | uM | LJP6 | 72 | hr | 1209 | 2242 | 4012 | 0.5591 | 0.4288 |
| MCF7 | Geldanamycin | 0.12 | uM | LJP5 | 72 | hr | 1209 | 1510 | 4203 | 0.3578 | 0.1249 |
| MCF7 | Geldanamycin | 0.12 | uM | LJP6 | 72 | hr | 1209 | 1405 | 4012 | 0.3500 | 0.0891 |