LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | CGP60474 | 10 | uM | LJP6 | 72 | hr | 1209 | 474 | 4012 | 0.1186 | -0.4179 |
| MCF7 | PD173074 | 0.04 | uM | LJP6 | 72 | hr | 1209 | 4081 | 4012 | 1.0185 | 1.0223 |
| MCF7 | PD173074 | 0.12 | uM | LJP6 | 72 | hr | 1209 | 4168 | 4012 | 1.0410 | 1.0482 |
| MCF7 | PD173074 | 0.37 | uM | LJP6 | 72 | hr | 1209 | 3920 | 4012 | 0.9790 | 0.9756 |
| MCF7 | PD173074 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 4272 | 4012 | 1.0660 | 1.0763 |
| MCF7 | PD173074 | 3.33 | uM | LJP6 | 72 | hr | 1209 | 3926 | 4012 | 0.9796 | 0.9771 |
| MCF7 | PD173074 | 10 | uM | LJP6 | 72 | hr | 1209 | 2693 | 4012 | 0.6724 | 0.5897 |
| MCF7 | Crizotinib | 0.04 | uM | LJP5 | 72 | hr | 1209 | 3621 | 4203 | 0.8617 | 0.8409 |
| MCF7 | Crizotinib | 0.12 | uM | LJP5 | 72 | hr | 1209 | 3523 | 4203 | 0.8394 | 0.8147 |
| MCF7 | Crizotinib | 0.37 | uM | LJP5 | 72 | hr | 1209 | 3073 | 4203 | 0.7306 | 0.6782 |
| MCF7 | Crizotinib | 1.11 | uM | LJP5 | 72 | hr | 1209 | 2163 | 4203 | 0.5141 | 0.3796 |
| MCF7 | Crizotinib | 3.33 | uM | LJP5 | 72 | hr | 1209 | 1299 | 4203 | 0.3095 | 0.0403 |
| MCF7 | Crizotinib | 10 | uM | LJP5 | 72 | hr | 1209 | 886 | 4203 | 0.2113 | -0.1594 |
| MCF7 | BMS345541 | 0.04 | uM | LJP6 | 72 | hr | 1209 | 4237 | 4012 | 1.0560 | 1.0640 |
| MCF7 | BMS345541 | 0.12 | uM | LJP6 | 72 | hr | 1209 | 3947 | 4012 | 0.9858 | 0.9846 |
| MCF7 | BMS345541 | 0.37 | uM | LJP6 | 72 | hr | 1209 | 3399 | 4012 | 0.8469 | 0.8161 |
| MCF7 | BMS345541 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 2502 | 4012 | 0.6224 | 0.5177 |
| MCF7 | BMS345541 | 3.33 | uM | LJP6 | 72 | hr | 1209 | 1427 | 4012 | 0.3561 | 0.1001 |
| MCF7 | BMS345541 | 10 | uM | LJP6 | 72 | hr | 1209 | 503 | 4012 | 0.1253 | -0.3986 |
| MCF7 | KIN001-043 | 0.04 | uM | LJP6 | 72 | hr | 1209 | 3628 | 4012 | 0.9066 | 0.8906 |
| MCF7 | KIN001-043 | 0.12 | uM | LJP6 | 72 | hr | 1209 | 3261 | 4012 | 0.8153 | 0.7776 |
| MCF7 | KIN001-043 | 0.37 | uM | LJP6 | 72 | hr | 1209 | 3159 | 4012 | 0.7893 | 0.7448 |
| MCF7 | KIN001-043 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 3378 | 4012 | 0.8427 | 0.8119 |
| MCF7 | KIN001-043 | 3.33 | uM | LJP6 | 72 | hr | 1209 | 3126 | 4012 | 0.7808 | 0.7336 |
| MCF7 | KIN001-043 | 10 | uM | LJP6 | 72 | hr | 1209 | 1613 | 4012 | 0.4027 | 0.1816 |