LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 GSK1059615
0.04
uM
LJP5
 72
hr
 1209 3973 4203 0.9462 0.9399
MCF7 GSK1059615
0.04
uM
LJP6
 72
hr
 1209 3764 4012 0.9401 0.9300
MCF7 GSK1059615
0.12
uM
LJP5
 72
hr
 1209 3526 4203 0.8395 0.8144
MCF7 GSK1059615
0.12
uM
LJP6
 72
hr
 1209 3368 4012 0.8399 0.8082
MCF7 GSK1059615
0.37
uM
LJP5
 72
hr
 1209 2627 4203 0.6260 0.5408
MCF7 GSK1059615
0.37
uM
LJP6
 72
hr
 1209 2825 4012 0.7044 0.6328
MCF7 GSK1059615
1.11
uM
LJP5
 72
hr
 1209 1448 4203 0.3453 0.1057
MCF7 GSK1059615
1.11
uM
LJP6
 72
hr
 1209 1785 4012 0.4452 0.2523
MCF7 GSK1059615
3.33
uM
LJP5
 72
hr
 1209 1029 4203 0.2447 -0.0877
MCF7 GSK1059615
3.33
uM
LJP6
 72
hr
 1209 986 4012 0.2453 -0.1134
MCF7 GSK1059615
10
uM
LJP5
 72
hr
 1209 664 4203 0.1578 -0.2854
MCF7 GSK1059615
10
uM
LJP6
 72
hr
 1209 793 4012 0.1971 -0.2200
MCF7 Brivanib
0.04
uM
LJP5
 72
hr
 1209 4167 4203 0.9925 0.9916
MCF7 Brivanib
0.12
uM
LJP5
 72
hr
 1209 3892 4203 0.9250 0.9137
MCF7 Brivanib
0.37
uM
LJP5
 72
hr
 1209 3943 4203 0.9385 0.9308
MCF7 Brivanib
1.11
uM
LJP5
 72
hr
 1209 3997 4203 0.9494 0.9410
MCF7 Brivanib
3.33
uM
LJP5
 72
hr
 1209 4047 4203 0.9636 0.9591
MCF7 Brivanib
10
uM
LJP5
 72
hr
 1209 3821 4203 0.9091 0.8963
MCF7 CHIR-99021
0.04
uM
LJP6
 72
hr
 1209 3736 4012 0.9315 0.9200
MCF7 CHIR-99021
0.12
uM
LJP6
 72
hr
 1209 3607 4012 0.9002 0.8826
MCF7 CHIR-99021
0.37
uM
LJP6
 72
hr
 1209 3606 4012 0.8988 0.8803
MCF7 CHIR-99021
1.11
uM
LJP6
 72
hr
 1209 3242 4012 0.8082 0.7683
MCF7 CHIR-99021
3.33
uM
LJP6
 72
hr
 1209 3034 4012 0.7552 0.6989
MCF7 CHIR-99021
10
uM
LJP6
 72
hr
 1209 1880 4012 0.4689 0.2901
MCF7 Linifanib
0.04
uM
LJP6
 72
hr
 1209 4004 4012 0.9976 0.9968