LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 Neratinib
1.11
uM
LJP5
 72
hr
 1209 1594 4203 0.3800 0.1664
MCF7 Neratinib
3.33
uM
LJP5
 72
hr
 1209 1390 4203 0.3315 0.0809
MCF7 Neratinib
10
uM
LJP5
 72
hr
 1209 1377 4203 0.3283 0.0751
MCF7 JW-7-24-1
0.04
uM
LJP6
 72
hr
 1209 2904 4012 0.7236 0.6583
MCF7 JW-7-24-1
0.12
uM
LJP6
 72
hr
 1209 2618 4012 0.6523 0.5618
MCF7 JW-7-24-1
0.37
uM
LJP6
 72
hr
 1209 2084 4012 0.5201 0.3704
MCF7 JW-7-24-1
1.11
uM
LJP6
 72
hr
 1209 1633 4012 0.4082 0.1901
MCF7 JW-7-24-1
3.33
uM
LJP6
 72
hr
 1209 1326 4012 0.3306 0.0542
MCF7 JW-7-24-1
10
uM
LJP6
 72
hr
 1209 937 4012 0.2339 -0.1376
MCF7 Dasatinib
0.04
uM
LJP5
 72
hr
 1209 3206 4203 0.7621 0.7182
MCF7 Dasatinib
0.04
uM
LJP6
 72
hr
 1209 1642 4012 0.4094 0.1929
MCF7 Dasatinib
0.12
uM
LJP5
 72
hr
 1209 2258 4203 0.5386 0.4170
MCF7 Dasatinib
0.12
uM
LJP6
 72
hr
 1209 1521 4012 0.3786 0.1395
MCF7 Dasatinib
0.37
uM
LJP5
 72
hr
 1209 1636 4203 0.3904 0.1839
MCF7 Dasatinib
0.37
uM
LJP6
 72
hr
 1209 1671 4012 0.4174 0.2064
MCF7 Dasatinib
1.11
uM
LJP5
 72
hr
 1209 1495 4203 0.3557 0.1241
MCF7 Dasatinib
1.11
uM
LJP6
 72
hr
 1209 1591 4012 0.3971 0.1721
MCF7 Dasatinib
3.33
uM
LJP5
 72
hr
 1209 1616 4203 0.3852 0.1753
MCF7 Dasatinib
3.33
uM
LJP6
 72
hr
 1209 1545 4012 0.3848 0.1507
MCF7 Dasatinib
10
uM
LJP5
 72
hr
 1209 1660 4203 0.3954 0.1920
MCF7 Dasatinib
10
uM
LJP6
 72
hr
 1209 1231 4012 0.3069 0.0089
MCF7 Tozasertib
0.04
uM
LJP5
 72
hr
 1209 1353 4203 0.3225 0.0646
MCF7 Tozasertib
0.12
uM
LJP5
 72
hr
 1209 1412 4203 0.3362 0.0895
MCF7 Tozasertib
0.37
uM
LJP5
 72
hr
 1209 1406 4203 0.3343 0.0857
MCF7 Tozasertib
1.11
uM
LJP5
 72
hr
 1209 1441 4203 0.3433 0.1021