LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | GW843682X | 0.37 | uM | LJP6 | 72 | hr | 1209 | 1487 | 4012 | 0.3704 | 0.1255 |
| MCF7 | GW843682X | 1.11 | uM | LJP6 | 72 | hr | 1209 | 1367 | 4012 | 0.3408 | 0.0727 |
| MCF7 | GW843682X | 3.33 | uM | LJP6 | 72 | hr | 1209 | 1310 | 4012 | 0.3271 | 0.0475 |
| MCF7 | GW843682X | 10 | uM | LJP6 | 72 | hr | 1209 | 1812 | 4012 | 0.4542 | 0.2646 |
| MCF7 | HG-5-113-01 | 0.04 | uM | LJP5 | 72 | hr | 1209 | 3957 | 4203 | 0.9412 | 0.9334 |
| MCF7 | HG-5-113-01 | 0.12 | uM | LJP5 | 72 | hr | 1209 | 3723 | 4203 | 0.8869 | 0.8705 |
| MCF7 | HG-5-113-01 | 0.37 | uM | LJP5 | 72 | hr | 1209 | 2153 | 4203 | 0.5125 | 0.3779 |
| MCF7 | HG-5-113-01 | 1.11 | uM | LJP5 | 72 | hr | 1209 | 1448 | 4203 | 0.3457 | 0.1064 |
| MCF7 | HG-5-113-01 | 3.33 | uM | LJP5 | 72 | hr | 1209 | 1316 | 4203 | 0.3136 | 0.0480 |
| MCF7 | HG-5-113-01 | 10 | uM | LJP5 | 72 | hr | 1209 | 569 | 4203 | 0.1358 | -0.3430 |
| MCF7 | HG-5-88-01 | 0.04 | uM | LJP6 | 72 | hr | 1209 | 3074 | 4012 | 0.7659 | 0.7136 |
| MCF7 | HG-5-88-01 | 0.12 | uM | LJP6 | 72 | hr | 1209 | 2824 | 4012 | 0.7038 | 0.6321 |
| MCF7 | HG-5-88-01 | 0.37 | uM | LJP6 | 72 | hr | 1209 | 2441 | 4012 | 0.6082 | 0.4996 |
| MCF7 | HG-5-88-01 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 2215 | 4012 | 0.5515 | 0.4167 |
| MCF7 | HG-5-88-01 | 3.33 | uM | LJP6 | 72 | hr | 1209 | 1982 | 4012 | 0.4938 | 0.3291 |
| MCF7 | HG-5-88-01 | 10 | uM | LJP6 | 72 | hr | 1209 | 958 | 4012 | 0.2393 | -0.1258 |
| MCF7 | HG-6-64-01 | 0.04 | uM | LJP6 | 72 | hr | 1209 | 4320 | 4012 | 1.0763 | 1.0866 |
| MCF7 | HG-6-64-01 | 0.12 | uM | LJP6 | 72 | hr | 1209 | 3908 | 4012 | 0.9731 | 0.9676 |
| MCF7 | HG-6-64-01 | 0.37 | uM | LJP6 | 72 | hr | 1209 | 4185 | 4012 | 1.0435 | 1.0500 |
| MCF7 | HG-6-64-01 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 4174 | 4012 | 1.0404 | 1.0464 |
| MCF7 | HG-6-64-01 | 3.33 | uM | LJP6 | 72 | hr | 1209 | 3307 | 4012 | 0.8205 | 0.7759 |
| MCF7 | HG-6-64-01 | 10 | uM | LJP6 | 72 | hr | 1209 | 170 | 4012 | 0.0422 | -0.6806 |
| MCF7 | Neratinib | 0.04 | uM | LJP5 | 72 | hr | 1209 | 3690 | 4203 | 0.8761 | 0.8552 |
| MCF7 | Neratinib | 0.12 | uM | LJP5 | 72 | hr | 1209 | 3310 | 4203 | 0.7868 | 0.7488 |
| MCF7 | Neratinib | 0.37 | uM | LJP5 | 72 | hr | 1209 | 2753 | 4203 | 0.6563 | 0.5821 |