LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Sorafenib | 0.12 | uM | LJP6 | 72 | hr | 1209 | 3886 | 4012 | 0.9700 | 0.9661 |
| MCF7 | Sorafenib | 0.37 | uM | LJP6 | 72 | hr | 1209 | 3825 | 4012 | 0.9544 | 0.9474 |
| MCF7 | Sorafenib | 1.11 | uM | LJP6 | 72 | hr | 1209 | 3953 | 4012 | 0.9866 | 0.9852 |
| MCF7 | Sorafenib | 3.33 | uM | LJP6 | 72 | hr | 1209 | 3843 | 4012 | 0.9590 | 0.9528 |
| MCF7 | Sorafenib | 10 | uM | LJP6 | 72 | hr | 1209 | 2138 | 4012 | 0.5330 | 0.3897 |
| MCF7 | CP466722 | 0.04 | uM | LJP5 | 72 | hr | 1209 | 4412 | 4203 | 1.0522 | 1.0586 |
| MCF7 | CP466722 | 0.12 | uM | LJP5 | 72 | hr | 1209 | 4175 | 4203 | 0.9932 | 0.9920 |
| MCF7 | CP466722 | 0.37 | uM | LJP5 | 72 | hr | 1209 | 4156 | 4203 | 0.9898 | 0.9893 |
| MCF7 | CP466722 | 1.11 | uM | LJP5 | 72 | hr | 1209 | 3824 | 4203 | 0.9113 | 0.8991 |
| MCF7 | CP466722 | 3.33 | uM | LJP5 | 72 | hr | 1209 | 3332 | 4203 | 0.7963 | 0.7620 |
| MCF7 | CP466722 | 10 | uM | LJP5 | 72 | hr | 1209 | 1742 | 4203 | 0.4146 | 0.2244 |
| MCF7 | CP724714 | 0.04 | uM | LJP5 | 72 | hr | 1209 | 3813 | 4203 | 0.9088 | 0.8972 |
| MCF7 | CP724714 | 0.12 | uM | LJP5 | 72 | hr | 1209 | 3746 | 4203 | 0.8906 | 0.8736 |
| MCF7 | CP724714 | 0.37 | uM | LJP5 | 72 | hr | 1209 | 3529 | 4203 | 0.8399 | 0.8145 |
| MCF7 | CP724714 | 1.11 | uM | LJP5 | 72 | hr | 1209 | 3699 | 4203 | 0.8820 | 0.8656 |
| MCF7 | CP724714 | 3.33 | uM | LJP5 | 72 | hr | 1209 | 3762 | 4203 | 0.8966 | 0.8829 |
| MCF7 | CP724714 | 10 | uM | LJP5 | 72 | hr | 1209 | 2778 | 4203 | 0.6601 | 0.5857 |
| MCF7 | Alvocidib | 0.04 | uM | LJP6 | 72 | hr | 1209 | 673 | 4012 | 0.1682 | -0.2872 |
| MCF7 | Alvocidib | 0.12 | uM | LJP6 | 72 | hr | 1209 | 624 | 4012 | 0.1556 | -0.3184 |
| MCF7 | Alvocidib | 0.37 | uM | LJP6 | 72 | hr | 1209 | 643 | 4012 | 0.1602 | -0.3067 |
| MCF7 | Alvocidib | 1.11 | uM | LJP6 | 72 | hr | 1209 | 652 | 4012 | 0.1628 | -0.3006 |
| MCF7 | Alvocidib | 3.33 | uM | LJP6 | 72 | hr | 1209 | 694 | 4012 | 0.1731 | -0.2752 |
| MCF7 | Alvocidib | 10 | uM | LJP6 | 72 | hr | 1209 | 679 | 4012 | 0.1700 | -0.2838 |
| MCF7 | GW843682X | 0.04 | uM | LJP6 | 72 | hr | 1209 | 2523 | 4012 | 0.6295 | 0.5304 |
| MCF7 | GW843682X | 0.12 | uM | LJP6 | 72 | hr | 1209 | 1614 | 4012 | 0.4023 | 0.1810 |