LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 GSK1904529A
0.37
uM
LJP6
 72
hr
 1209 2171 4012 0.5425 0.4041
MCF7 GSK1904529A
1.11
uM
LJP6
 72
hr
 1209 2046 4012 0.5101 0.3549
MCF7 GSK1904529A
3.33
uM
LJP6
 72
hr
 1209 1999 4012 0.4988 0.3374
MCF7 GSK1904529A
10
uM
LJP6
 72
hr
 1209 1997 4012 0.4988 0.3375
MCF7 Linsitinib
0.04
uM
LJP5
 72
hr
 1209 3271 4203 0.7776 0.7377
MCF7 Linsitinib
0.12
uM
LJP5
 72
hr
 1209 2975 4203 0.7074 0.6482
MCF7 Linsitinib
0.37
uM
LJP5
 72
hr
 1209 2335 4203 0.5554 0.4407
MCF7 Linsitinib
1.11
uM
LJP5
 72
hr
 1209 2053 4203 0.4890 0.3419
MCF7 Linsitinib
3.33
uM
LJP5
 72
hr
 1209 1932 4203 0.4600 0.2976
MCF7 Linsitinib
10
uM
LJP5
 72
hr
 1209 1647 4203 0.3926 0.1877
MCF7 Ruxolitinib
0.04
uM
LJP5
 72
hr
 1209 4326 4203 1.0260 1.0237
MCF7 Ruxolitinib
0.12
uM
LJP5
 72
hr
 1209 4206 4203 1.0013 1.0020
MCF7 Ruxolitinib
0.37
uM
LJP5
 72
hr
 1209 4219 4203 1.0039 1.0043
MCF7 Ruxolitinib
1.11
uM
LJP5
 72
hr
 1209 4523 4203 1.0753 1.0811
MCF7 Ruxolitinib
3.33
uM
LJP5
 72
hr
 1209 4523 4203 1.0761 1.0827
MCF7 Ruxolitinib
10
uM
LJP5
 72
hr
 1209 3462 4203 0.8236 0.7938
MCF7 Momelotinib
0.04
uM
LJP5
 72
hr
 1209 3799 4203 0.9044 0.8912
MCF7 Momelotinib
0.12
uM
LJP5
 72
hr
 1209 3956 4203 0.9422 0.9353
MCF7 Momelotinib
0.37
uM
LJP5
 72
hr
 1209 3620 4203 0.8624 0.8424
MCF7 Momelotinib
1.11
uM
LJP5
 72
hr
 1209 2752 4203 0.6544 0.5782
MCF7 Momelotinib
3.33
uM
LJP5
 72
hr
 1209 1704 4203 0.4057 0.2098
MCF7 Momelotinib
10
uM
LJP5
 72
hr
 1209 1263 4203 0.3000 0.0219
MCF7 Fedratinib
0.04
uM
LJP5
 72
hr
 1209 4036 4203 0.9615 0.9563
MCF7 Fedratinib
0.12
uM
LJP5
 72
hr
 1209 3749 4203 0.8898 0.8710
MCF7 Fedratinib
0.37
uM
LJP5
 72
hr
 1209 3198 4203 0.7612 0.7177