LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 Dovitinib
0.12
uM
LJP5
 72
hr
 1209 3885 4203 0.9251 0.9153
MCF7 Dovitinib
0.37
uM
LJP5
 72
hr
 1209 2707 4203 0.6441 0.5634
MCF7 Dovitinib
1.11
uM
LJP5
 72
hr
 1209 2067 4203 0.4912 0.3450
MCF7 Dovitinib
3.33
uM
LJP5
 72
hr
 1209 1690 4203 0.4021 0.2035
MCF7 Dovitinib
10
uM
LJP5
 72
hr
 1209 1654 4203 0.3937 0.1895
MCF7 GSK 690693
0.04
uM
LJP5
 72
hr
 1209 2794 4203 0.6647 0.5926
MCF7 GSK 690693
0.12
uM
LJP5
 72
hr
 1209 2286 4203 0.5448 0.4261
MCF7 GSK 690693
0.37
uM
LJP5
 72
hr
 1209 2009 4203 0.4779 0.3243
MCF7 GSK 690693
1.11
uM
LJP5
 72
hr
 1209 1923 4203 0.4582 0.2947
MCF7 GSK 690693
3.33
uM
LJP5
 72
hr
 1209 1828 4203 0.4359 0.2593
MCF7 GSK 690693
10
uM
LJP5
 72
hr
 1209 1699 4203 0.4048 0.2084
MCF7 SNS-032
0.04
uM
LJP6
 72
hr
 1209 1200 4012 0.2993 -0.0048
MCF7 SNS-032
0.12
uM
LJP6
 72
hr
 1209 734 4012 0.1835 -0.2505
MCF7 SNS-032
0.37
uM
LJP6
 72
hr
 1209 723 4012 0.1801 -0.2581
MCF7 SNS-032
1.11
uM
LJP6
 72
hr
 1209 720 4012 0.1798 -0.2592
MCF7 SNS-032
3.33
uM
LJP6
 72
hr
 1209 702 4012 0.1752 -0.2704
MCF7 SNS-032
10
uM
LJP6
 72
hr
 1209 694 4012 0.1730 -0.2754
MCF7 Afatinib
0.04
uM
LJP6
 72
hr
 1209 3665 4012 0.9147 0.9003
MCF7 Afatinib
0.12
uM
LJP6
 72
hr
 1209 3666 4012 0.9160 0.9019
MCF7 Afatinib
0.37
uM
LJP6
 72
hr
 1209 3723 4012 0.9287 0.9168
MCF7 Afatinib
1.11
uM
LJP6
 72
hr
 1209 2817 4012 0.7008 0.6263
MCF7 Afatinib
3.33
uM
LJP6
 72
hr
 1209 3086 4012 0.7711 0.7213
MCF7 Afatinib
10
uM
LJP6
 72
hr
 1209 922 4012 0.2304 -0.1451
MCF7 GSK1904529A
0.04
uM
LJP6
 72
hr
 1209 2379 4012 0.5937 0.4795
MCF7 GSK1904529A
0.12
uM
LJP6
 72
hr
 1209 2269 4012 0.5660 0.4382