LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 AZD-6482
3.33
uM
LJP5
 72
hr
 1209 3144 4203 0.7492 0.7033
MCF7 AZD-6482
10
uM
LJP5
 72
hr
 1209 1478 4203 0.3503 0.1121
MCF7 NU7441
0.04
uM
LJP5
 72
hr
 1209 4014 4203 0.9547 0.9482
MCF7 NU7441
0.12
uM
LJP5
 72
hr
 1209 3929 4203 0.9360 0.9282
MCF7 NU7441
0.37
uM
LJP5
 72
hr
 1209 3777 4203 0.8990 0.8849
MCF7 NU7441
1.11
uM
LJP5
 72
hr
 1209 3487 4203 0.8305 0.8038
MCF7 NU7441
3.33
uM
LJP5
 72
hr
 1209 3054 4203 0.7274 0.6752
MCF7 NU7441
10
uM
LJP5
 72
hr
 1209 1259 4203 0.2999 0.0219
MCF7 OSI-027
0.04
uM
LJP6
 72
hr
 1209 3192 4012 0.7973 0.7551
MCF7 OSI-027
0.12
uM
LJP6
 72
hr
 1209 2358 4012 0.5890 0.4727
MCF7 OSI-027
0.37
uM
LJP6
 72
hr
 1209 1958 4012 0.4893 0.3225
MCF7 OSI-027
1.11
uM
LJP6
 72
hr
 1209 1612 4012 0.4026 0.1810
MCF7 OSI-027
3.33
uM
LJP6
 72
hr
 1209 1459 4012 0.3648 0.1153
MCF7 OSI-027
10
uM
LJP6
 72
hr
 1209 1255 4012 0.3130 0.0214
MCF7 WYE-125132
0.04
uM
LJP6
 72
hr
 1209 1334 4012 0.3324 0.0570
MCF7 WYE-125132
0.12
uM
LJP6
 72
hr
 1209 1264 4012 0.3151 0.0251
MCF7 WYE-125132
0.37
uM
LJP6
 72
hr
 1209 1318 4012 0.3286 0.0505
MCF7 WYE-125132
1.11
uM
LJP6
 72
hr
 1209 1292 4012 0.3221 0.0383
MCF7 WYE-125132
3.33
uM
LJP6
 72
hr
 1209 1170 4012 0.2922 -0.0187
MCF7 WYE-125132
10
uM
LJP6
 72
hr
 1209 879 4012 0.2192 -0.1689
MCF7 Barasertib
0.04
uM
LJP5
 72
hr
 1209 1502 4203 0.3579 0.1279
MCF7 Barasertib
0.12
uM
LJP5
 72
hr
 1209 1458 4203 0.3476 0.1101
MCF7 Barasertib
0.37
uM
LJP5
 72
hr
 1209 1454 4203 0.3463 0.1077
MCF7 Barasertib
1.11
uM
LJP5
 72
hr
 1209 1417 4203 0.3379 0.0926
MCF7 Barasertib
3.33
uM
LJP5
 72
hr
 1209 1407 4203 0.3358 0.0887